摘要
1例37岁女性患者,妊娠中期出现急性肾损伤、无尿、血小板减少和微血管病性溶血性贫血,CFHR3基因突变,诊断为妊娠相关非典型溶血性尿毒综合征(P-aHUS),经激素、依库珠单抗和血液透析治疗后脱离透析,肾功能恢复,血小板正常,为P-aHUS的治疗提供新的思路和参考。
This article retrospectively analyzed the diagnosis and treatment of a patient with pregnancy-related atypical hemolytic uremic syndrome(P-aHUS)admitted to Sichuan Provincial People'Hospital,and reviewed the literature.This patient developed acute renal failure,anuria,thrombocytopenia,and microangiopathic hemolytic anemia in the second trimester of pregnancy.She had CFHR3 gene mutation and was diagnosed as pregnancy-related atypical hemolytic-uremic syndrome.After treatment with steroids,eculizumab,and dialysis,the kidney function recovered and platelets became normal,which provides new ideas and references for the treatment of pregnancy-related hemolytic uremic syndrome.
作者
钱小方
李贵森
王蔚
陈莎莎
QIAN Xiaofang;LI Guisen;WANG Wei;CHEN Shasha(Department of Nephology,Chengdu Shuangliu Hospital of Traditional Chinese Medicine,Chengdu 610200,China;Department of Nephrology,Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital,Chengdu 610072,China)
出处
《肾脏病与透析肾移植杂志》
2025年第4期395-400,共6页
Chinese Journal of Nephrology,Dialysis & Transplantation
