摘要
报告胫前粘液性水肿1例。患者男,66岁,因双下肢胫前皮肤硬肿3年就诊。皮肤科检查:双侧小腿胫前中下部、足背可见非凹陷性、水肿型斑块,皮肤硬肿,增厚明显,弹性变差。皮损组织病理检查:表皮角化过度,真皮内胶原纤维间大量黏蛋白沉积。AB-PAS染色阳性。诊断:胫前粘液性水肿。予糖皮质激素皮损内注射治疗,3个月后随访,患者双下肢胫前皮肤硬肿程度较前明显缓解。
We report a case of pretibial myxedema.A 66-year-old man presented with skin induration on the anterior tibia of both lower limbs for 3 years.Dermatological examination showed non-pitting,edematous plaques on the anterior,middle and lower tibia of the lower leg and the dorsal feet.The skin was indurated,significantly thickened,and reduced elasticity.Histopathological examination of skin lesions revealed chronic inflammation with edema and abundant mucin deposition between collagen fibers in the dermis.AB-PAS staining was positive.The patient was diagnosed with pretibial myxedema.The patient was treated with intralesional injections of glucocorticoids.At the 3-month follow-up,the induration and edema of the anterior tibial skin on both lower limbs had significantly improved.
作者
曹志成
李晶冰
CAO Zhicheng;LI Jingbing(Xuzhou Central Hospital,Xuzhou 221000,China)
出处
《皮肤性病诊疗学杂志》
2025年第8期594-597,共4页
Journal of Diagnosis and Therapy on Dermato-venereology
