摘要
目的探讨超声引导下真空辅助微创切除术(VAE)治疗乳腺良性分叶状肿瘤的安全性与有效性。方法回顾性分析2016年6月至2023年12月江苏大学附属宜兴医院收治的170例乳腺良性分叶状肿瘤患者临床资料。根据手术方式分为VAE组和开放手术组(OE),采用倾向性评分匹配法平衡两组基线特征。比较两组患者的临床特征、局部复发率、围手术期数据。结果匹配前共纳入170例患者(VAE组88例,OE组82例);匹配后两组各59例,基线资料均衡,差异无统计学意义。中位随访时间28.5(1~91)个月,两组局部复发率均为16.9%。在术后2年内(Log-rank P=0.415)、术后超过2年(Log-rank P=0.062)分段,VAE组与OE组的累积无复发生存率差异均无统计学意义。与OE组相比,VAE组的切口长度缩短,术后数字评分量表评分降低,但住院费用明显增加(P<0.05)。结论VAE与OE在乳腺良性分叶状肿瘤患者中具有相近的无复发生存期,是良性分叶状肿瘤的微创治疗选择。
Objective To explore the safety and efficacy of ultrasound-guided vacuum-assisted excision(VAE)in the treatment of benign phyllodes tumor of the breast.Methods The clinical data of 170 patients with benign phyllodes tumor of the breast admitted to Yixing Hospital Affiliated to Jiangsu University from June 2016 to December 2023 were retrospectively analyzed.The patients were divided into the VAE group and the open excision(OE)group according to the surgical method.Propensity score matching was used to balance the baseline characteristics of the two groups.The clinical characteristics,local recurrence rate,and perioperative data of the two groups were compared.Results A total of 170 patients were included before matching(88 in the VAE group and 82 in the OE group);after matching,there were 59 patients in each group,and the baseline data were balanced.The median follow-up period was 28.5(1-91)months.The local recurrence rate was 16.9%in both groups.There was no statistically significant difference in the cumulative recurrence-free survival rate between the VAE group and the OE group within 2 years after surgery(Log-rank P=0.415)or more than 2 years after surgery(Log-rank P=0.062).Compared with the OE group,the VAE group had shorter incision length,lower score of numeric rating scale,but significantly higher hospitalization costs(P<0.05).Conclusion VAE and OE have similar recurrence-free survival periods in patients with benign phyllodes tumor of the breast and are both minimally invasive treatment options for benign phyllodes tumor.
作者
严孟欣
朱星瑀
陈翔
Yan Mengxin;Zhu Xingyu;Chen Xiang(Department of Thyroid and Breast Surgery,Yixing Hospital Affiliated to Jiangsu University,Wuxi 214205,China)
出处
《中华普通外科学文献(电子版)》
2025年第4期269-273,共5页
Chinese Archives of General Surgery(Electronic Edition)
