摘要
目的:观察目标导向镇静策略(EGDS)干预对重症患者多导睡眠监测下睡眠结构的影响。方法:选取2022年10月至2024年10月厦门大学附属第一医院收治的重症监护室患者90例作为研究对象,按照随机数字表法分为对照组和观察组,每组45例。对照组予以常规镇静干预,观察组予以EGDS干预。通过匹兹堡睡眠质量指数(PSQI)以及多导睡眠图(PSG)睡眠结构比较2组睡眠质量,通过机械通气持续时长、ICU留置时间及拔管时间比较临床指标。结果:观察组机械通气持续时长、ICU留置时间及拔管时间均优于对照组,差异有统计学意义(P<0.05);干预3 d后,观察组PSG检测中不同睡眠阶段时长比例:快速动眼期/有效睡眠(REM%)、睡眠效率(SE)、N1期/有效睡眠(N1%)、N2期/有效睡眠(N2%)和N3期/有效睡眠(N3%)均较对照组更优,差异有统计学意义(P<0.05);干预3 d后,观察组PSQI量表评估,睡眠质量、睡眠障碍、入睡时间和睡眠时间分值均较对照组低,差异有统计学意义(P<0.05)。结论:EGDS干预可促进重症患者睡眠结构与睡眠质量改善,并且缩短患者康复时间。
Objective:To observe the effects of early goal-directed strategy(EGDS)on Sleep architecture in critically ill patients monitored by polysomnography(PSG).Methods:A total of 90 patients admitted to the intensive care unit of the hospital were enrolled as the research objects between October 2022 and October 2024.According to random number table method,they were divided into observation group(EGDS)and control group(routine sedation),45 cases in each group.The sleep quality[Pittsburgh Sleep Quality Index(PSQI),Sleep architecture under PSG]and clinical indexes(duration of mechanical ventilation,stay time in ICU,extubation time)were compared between the two groups before and after intervention.Results:The clinical indexes in the observation group were better than those in the control group(P<0.05).After 3 d of intervention,rapid eye movement/effective sleep%(REM%),sleep efficiency(SE),stage N1/effective sleep%(N1%),stage N2/effective sleep%(N2%)and stage N3/effective sleep%(N3%)in observation group were better than those in control group(P<0.05).After 3 d of intervention,scores of PSQI(sleep quality,sleep disturbance,falling asleep time,sleep time)in the observation group were higher than those in the control group(P<0.05).Conclusion:EGDS intervention improves sleep architecture and quality while accelerating recovery in critically ill patients.
作者
曾雪玲
黄洋洋
ZENG Xueling;HUANG Yangyang(Department of Critical Care Medicine,The First Affiliated Hospital of Xiamen University,Xiamen 361000,China)
出处
《世界睡眠医学杂志》
2025年第5期1020-1022,1026,共4页
World Journal of Sleep Medicine
关键词
目标导向
镇静
重症患者
多导睡眠监测
睡眠结构
睡眠质量
Goal-directed
Sedation
Critically ill patients
Polysomnography monitoring
Sleep architecture
Sleep quality
