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内蒙古自治区呼和浩特市区16305例婴儿维生素D营养状况及影响因素分析

Analysis of vitamin D nutritional status of 16305 infants and its influencing factors in Hohhot City,Inner Mongolia Autonomous Region
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摘要 目的了解内蒙古自治区呼和浩特市婴儿维生素D营养状况,并分析其影响因素。方法选取于2021年1月—2023年12月到内蒙古自治区妇幼保健院接受健康体检的29 d~<12月足月健康婴儿,应用高灵敏度的电化学分析方法测定其25-(OH)D值,并对维生素D营养状况的影响因素进行分析。结果呼和浩特市婴儿维生素D平均值为(69.78±19.25)nmol/L,维生素D缺乏率为22.24%,不足率为32.85%。汉族婴儿维生素D平均值为(69.54±19.59)nmol/L,蒙古族婴儿维生素D平均值为(70.90±18.16)nmol/L。3月~<6月龄婴儿维生素D平均值(68.88±20.10)nmol/L明显低于其他年龄组(均P<0.05);在冬、春季进行检测的婴儿维生素D平均值分别为(69.76±17.99)nmol/L和(69.97±20.4)nmol/L,明显低于在夏季(70.55±18.23)nmol/L和秋季(70.55±18.23)nmol/L检测的婴儿(均P<0.05)。结论呼和浩特市婴儿维生素D缺乏或不足普遍存在,3月~<6月龄婴儿及冬季、春季维生素D营养水平相对较低,应根据季节变换及时有效地调整维生素D补充量,并依据血清维生素D水平制定个性化补充方案。 Objective To understand the vitamin D nutritional status of infants in Hohhot and analyze its influencing factors,providing theoretical guidance for the rational supplementation of vitamin D for infants.Methods Healthy infants aged 29 days to 12 months who underwent health check-ups at the Inner Mongolia Autonomous Region Maternal and Child Health Hospital from January 2021 to December 2021 were selected.High-performance liquid chromatography-tandem mass spectrometry(lc-msms)was used to measure the value of 25-(OH)D to indicate the nutritional status of vitamin D,and the influencing factors were analyzed.Results The average level of vitamin D in infants in Hohhot was(69.78±19.25)nmol/l,with a deficiency rate of 22.24%and an insufficiency rate of 32.85%.The average vitamin D level was(69.54±19.59)nmol/L for Han infants,(70.90±18.16)nmol/L for Mongols infants.The average vitamin D levels in infants aged 3-<6 months(68.88±20.10 nmol/L)were significantly lower than those in the other age groups(all P<0.05).The average vitamin D levels in infants tested during winter(69.76±17.99 nmol/L)and spring(69.97±20.4 nmol/L)were significantly lower than those tested in summer(70.55±18.23 nmol/L)and autumn(70.55±18.23 nmol/L)(all P<0.05).Conclusion Vitamin D deficiency or insufficiency is common among infants in Hohhot.The vitamin D nutrition levels of infants who aged 3-<6 months tested in winter and spring are relatively low.It is necessary to effectively and promptly adjust vitamin D supplementation according to the season,monitor serum vitamin D levels,and develop individualized supplementation plans.
作者 梁晓平 张玉玲 杨波 张慧如 刘雪波 LIANG Xiaoping;ZHANG Yuling;YANG Bo;ZHANG Huiru;LIU Xuebo(Inner Mongolia Autonomous Region Maternal and Child Health Hospital,Hohhot City 010020,Inner Mongolia Autonomous Region,China)
出处 《中国妇幼卫生杂志》 2025年第4期313-317,共5页 Chinese Journal of Women and Children Health
基金 内蒙古卫生健康科技项目(202202098)。
关键词 维生素D 营养状况 婴儿 影响因素 vitamin D nutritional status infant influencing factor
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