摘要
目的了解美沙酮维持治疗(MMT)门诊丙型肝炎病毒(HCV)抗体阳性者丙肝治疗相关影响因素,为制定有效的干预措施提供依据。方法以MMT门诊为研究现场,采用方便抽样方法收集MMT门诊HCV抗体阳性者的信息,分析其丙肝治疗情况及影响因素。结果共调查354人,40岁以上334例(94.35%);男性307例(86.72%);汉族351例(99.15%);待业/无业人员194例(54.80%);初中及以下学历284例(80.23%);在婚或同居176例(49.72%);非独居状态259例(73.16%)。接受过HCV核酸检测130例(36.72%),接受抗HCV治疗110例(31.07%)。Logistic回归分析结果显示,有酗酒史(OR=2.587)、家人知晓患病(OR=10.644)、家人动员治疗(OR=2.504)、丙肝知识认知程度较好(OR=1.919)、接受过HCV核酸检测(OR=2.857)、有医保(OR=2.995)的HCV抗体阳性者接受抗HCV治疗的概率更高;从事“其他”职业(OR=0.362)的HCV抗体阳性者接受抗HCV治疗的概率更低。结论广东省MMT门诊中HCV抗体阳性者接受抗HCV治疗的比例较低。建议加强健康教育,提升患者对丙肝的认知;鼓励家庭参与患者的健康管理并提供必要支持;同时,医疗机构应提供便捷的核酸检测服务,确保患者能够及时确诊和治疗。
Objective To understand the influencing factors related to hepatitis C treatment among methadone maintenance treatment(MMT)clinic patients with hepatitis C virus(HCV)antibody positivity,and to provide a basis for formulating effective intervention measures.Methods Using MMT clinics as the research site,a convenient sampling method was used to collect information from HCV antibody-positive individuals in MMT clinics,and their hepatitis C treatment status and influencing factors were analyzed.Results A total of 354 individuals were surveyed,with 334 cases(94.35%)aged 40 and above;307 cases(86.72%)were male;351 Han Chinese(99.15%);194 unemployed individuals(54.80%);284 with junior high school education or below(80.23%);176 married or cohabiting(49.72%);and 259 non-single-living individuals(73.16%).130 cases(36.72%)had received nucleic acid testing for hepatitis C virus,and 110 cases(31.07%)had received anti-HCV treatment.Logistic regression analysis results show that HCV antibody positive patients with a history of alcoholism(OR=2.587),family members aware of the illness(OR=10.644),family members encouraging treatment(OR=2.504),better awareness of hepatitis C knowledge(OR=1.919),having received nucleic acid testing for hepatitis C virus(OR=2.857),and having medical insurance(OR=2.995)were more likely to receive anti-HCV treatment;individuals with HCV antibody positivity engaged in"other"occupations(OR=0.362)have a lower probability of receiving anti-HCV treatment.Conclusion sIn Guangdong Province,the proportion of HCV antibody-positive individuals receiving anti-HCV treatment in MMT clinics is relatively low.To address this issue,the following measures are recommended:strengthen health education to improve patients'awareness of hepatitis C;encourage family involvement in patients'health management and provide necessary support;meanwhile,healthcare institutions should offer accessible nucleic acid testing services to ensure timely diagnosis and treatment for patients.
作者
郑洪清
潘丝媛
王国任
王丽荣
阮峰
方晓君
李艳
杨放
黎健荣
ZHENG Hongqing;PAN Siyuan;WANG Guoren;WANG Lirong;RUAN Feng;FANG Xiaojun;LI Yan;YANG Fang;LI Jianrong(Guangdong Provincial Field Epidemiology Training Program,Guangzhou,GuangDong 511430,China;Guangdong Provincial Center for Disease Control and Prevention;Heilongjiang Provincial Center for Disease Control and Prevention;Ganzi Tibetan Autonomous Prefecture Center for Disease Control and Prevention;Zhuhai Center for Disease Control and Prevention;Dongguan Center for Disease Control and Prevention)
出处
《华南预防医学》
2025年第6期627-631,637,共6页
South China Journal of Preventive Medicine
基金
广东省医学科研基金项目(A2021451)。
关键词
美沙酮维持治疗
HCV抗体阳性
丙型肝炎
影响因素
Methadone maintenance treatment
HCV antibody positive
Hepatitis C
Influencing factors
