摘要
目的研究旨在探讨飞秒激光制瓣的准分子激光原位角膜磨镶术(femtosecond laser LASIK,FS-LASIK)对屈光参差患者视觉质量的影响,并分析角膜厚度与散光度对术后效果的相关性。方法本研究纳入2023年1月至2023年10月期间的82例屈光参差患者,年龄18至45岁,男女比例为1∶1.2。所有患者在术前经过全面术前检查,符合屈光参差(屈光度差异大于1.00D)标准,并接受LASIK手术治疗。术后患者进行了至少6个月的随访,评估其裸眼视力(Uncorrected Visual Acuity,UCVA)、最佳矫正视力(Best Corrected Visual Acuity,BCVA)、角膜形态(角膜厚度与曲率)、眼压及眼部健康状况等指标。使用SPSS 25.0软件进行统计分析,采用皮尔逊相关分析和Logistic回归分析评估角膜厚度、散光度数与术后视觉质量之间的关系。结果所有患者在术后6个月内的裸眼视力(UCVA)显著改善,术后UCVA达到20/25及以上的患者占92%。最佳矫正视力(BCVA)亦有所提高,90%的患者术后BCVA达到20/20或更好。术后角膜厚度未出现过度切削,所有患者角膜厚度保持在450以上,角膜曲率变化均在±1.0D范围内,未出现角膜扩张。术后眼压维持在正常范围内,未发现青光眼或其他并发症。干眼症的发生率为15%,主要为轻度干眼。皮尔逊相关分析显示,角膜厚度与术后UCVA(r=0.68,P<0.01)以及散光度数与术后BCVA(r=0.62,P<0.01)呈显著正相关。Logistic回归分析显示角膜厚度对视力有正向影响,散光度数和干眼症状负向影响,术前视力为重要预测因素,其他因素如术后眼压、性别等影响较小。结论LASIK手术对屈光参差患者具有良好的矫正效果,术后视觉质量显著提高,角膜形态稳定,眼压正常。角膜厚度和散光度是影响术后视觉质量的重要因素。此研究为临床实践中屈光参差患者的手术选择提供了有价值的数据支持。
Objective The purpose of this study is to investigate the effect of femtosecond laser in situ keratomileu-sis(FS-LASIK)on the visual quality of patients with anisometropia,and to analyze the correlation between corneal thickness and astigmatism on postoperative outcomes.Methods This study included 82 patients with anisometropia from January 2023 to October 2023,aged 18 to 45 years,with a male to female ratio of 1:1.2.All patients underwent comprehensive preoperative examination and met the criteria for anisometropia(refractive error difference greater than 1.ooD),and underwent LASIK surgery for treatment.The postoperative patients were followed up for at least 6 months to evaluate their uncorrected visual acuity(UCVA),best corrected visual acuity(BCVA),corneal morphology(corneal thickness and curvature),intraocular pressure,and eye health status.Statistical analysis was conducted using SPSS 25.O software,and Pearson correlation analysis and logistic regression analysis were used to evaluate the relation-ship between corneal thickness,astigmatism,and postoperative visual quality.As a result,the uncorrected visual acuity(UCVA)of all patients significantly improved within 6 months after surgery,with 92%of patients achieving a postop-erative UCVA of 20/25 or higher.The best corrected visual acuity(BCVA)has also improved,with 90%of patients a-chieving a BCVA of 20/20 or better after surgery.There was no excessive cutting of corneal thickness after surgery,and the corneal thickness of all patients remained above 450.The corneal curvature changes were within±1.OD range,
作者
张珍珍
刘红杰
刘霞
崔燕
任延军
ZHANG Zhenzhen;LIU Hongjie;LIU Xia;CUI Yan;REN Yanjun(Re-fractive Surgery Department,Handan City Eye Hospital(The Third Hospital of Handan),Handan,Hebei 056001,China)
出处
《中国实验诊断学》
2025年第8期880-890,共11页
Chinese Journal of Laboratory Diagnosis
关键词
屈光参差
激光角膜屈光手术
角膜厚度
散光度数
Anisometropia
Laser corneal refractive surgery
Corneal thickness
Astigmatism degree
