摘要
目的 分析出生缺陷(birth defects,BDs)与产妇年龄相关性。方法 选取2012年1月至2021年12月分娩产妇21 543人次,BDs 789例作为研究对象,分析BDs发生率,利用Logistic回归分析模型分析BDs与产妇年龄的相关性。结果 十年间分娩量增加,经产妇及高龄产妇显著增加(P<0.05);分娩年龄越大,BDs发生率越高;高龄产妇染色体相关BDs发生率高;严重BDs的引产率有所下降。结论 产妇年龄是影响BDs的独立危险因素与BDs发生率成正比,落实BDs三级预防可有效降低严重BDs的发生率。
Objective To analyze the correlation of birth defects(BDs)and maternal age.Methods A total of 789 BDs cases among 21,543 postpartum women from January 2012 to December 2021 were selected as research objects.The baseline data and research data were included in SPSS21.0 software.The incidence of BDs was analyzed,and the correlation between BDs and maternal age was analyzed by logistic regression analysis.Results Over the past decade,the number of deliveries increased,with a significant increase in both postmenopausal and elderly women(P<0.05).The older the age of delivery,the higher the incidence of BDs.The incidence of older maternal chromosome-related BDs was high.The induction rate of severe BDs decreased.Conclusion Maternal age is an independent risk factor for BDs,and it is directly proportional to the incidence of BDs.Implementing three-level prevention of BDs can effectively reduce the incidence of severe BDs.
作者
郝静
杨悦
HAO Jing;YANG Yue(Department of Obstetrics and Gynecology,Civil Aviation General Hospital,Beijing 100037,China)
出处
《河北医药》
2025年第8期1383-1385,共3页
Hebei Medical Journal
关键词
出生缺陷
产妇年龄
相关性
引产
birth defects
maternal age
correlation
labor induction
