摘要
目的探讨联合电子聚焦式高能体外冲击波治疗强直性脊柱炎对疼痛、疾病活动度和炎症因子的影响。方法根据随机数字表法,将在2021年5月至2023年8月间于信阳淮河骨科医院就诊的69例强直性脊柱炎患者分为对照组(34例)和观察组(35例)。施以对照组单纯艾瑞昔布胶囊口服治疗,观察组在以上技术上加以电子聚焦式高能体外冲击波治疗。比较两组疼痛程度和晨僵时间;治疗前后疾病活动程度、炎性因子水平、腰椎功能。结果与治疗前相比较,两组治疗后及疗后一个月的VAS评分均有所降低,且观察组较对照组更低;两组晨僵时间均有所缩短,且观察组较对照组更短(P<0.05);但治疗一个月后两组VAS评分、晨僵时间与治疗后相比无明显差异(P>0.05)。与治疗前相比较,两组治疗后BASDAI、SPARCC评分均降低,且观察组较对照组更低;两组治疗后JOA评分均有所升高,且观察组较对照组更高(P<0.05)。与治疗前相比较,两组治疗后C-反应蛋白、血沉水平均有所降低,骨形态发生蛋白-2水平均有所升高,但两组之间比较无显著性差异(P>0.05)。与治疗前相比较,两组治疗后腰椎前屈、腰椎侧弯及腰椎后仰幅度均有所增大,且观察组增幅更大(P<0.05)。结论联合采用电子聚焦式高能体外冲击波治疗可迅速缓解强直性脊柱炎患者的疼痛程度,改善患者活动度与腰椎功能,且无创、安全性较高,具有较高的临床应用价值。
Objective To investigate the effects of combined electronic-focused high-energy extracorporeal shock wave therapy on ankylosing spondylitis(AS)in terms of pain,disease activity,and inflammatory markers.Methods Sixty-nine AS patients treated at Xinyang Huaihe Orthopedic Hospital between May 2021 and August 2023 were randomly divided into a control group(34 cases)and an observation group(35 cases)using a random number table method.The control group received oral irbesacib capsules alone,while the observation group received electronic-focused high-energy extracorporeal shock wave therapy in addition to oral medication.Pain severity and morning stiffness duration were compared between groups,along with disease activity levels,inflammatory marker levels,and lumbar function before and after treatment.Results Compared with baseline values,both groups showed reduced VAS scores post-treatment and one-month follow-up,with the observation group showing lower scores than the control group.Morning stiffness duration decreased in both groups,but the reduction was more pronounced in the observation group(P<0.05).However,no significant differences in VAS scores or morning stiffness duration were observed after one month of treatment(P>0.05).Baseline and post-treatment BASDAI and SPARCC scores decreased in both groups,with the observation group showing lower values than the control group.JOA scores increased in both groups,but the difference was not statistically significant(P<0.05).C-reactive protein and erythrocyte sedimentation rate levels decreased,while osteoforming protein-2 levels increased,though no significant differences were found between groups(P>0.05).Compared with pre-treatment measurements,both groups showed increased lumbar flexion,lateral curvature,and extension range after treatment,with the observation group demonstrating greater improvement(P<0.05).Conclusion The combined use of electronic-focused high-energy extracorporeal shock wave therapy can rapidly alleviate pain levels in ankylosing spondylitis patients,improve mobility and lumbar function,while being non-invasive and highly safe,making it clinically valuable for application.
作者
曹俊岭
李长恒
CAO Jun-ling;LI Chang-heng(Department of Orthopaedics 2,Xinyang Huaihe Orthopedic Hospital,Xinyang 464000,Henan Province,China)
出处
《罕少疾病杂志》
2025年第8期128-130,共3页
Journal of Rare and Uncommon Diseases
关键词
强直性脊柱炎
电子聚焦式高能体外冲击波
艾瑞昔布
疾病活动度
Ankylosing Spondylitis
Electronic Focused High-energy Extracorporeal Shock Wave
Airixib
Disease Activity
