摘要
目的基于logistic回归分析影响新生儿缺氧缺血性脑病营养状况的危险因素。方法回顾性分析136例缺氧缺血性脑病新生儿的临床资料,根据患儿营养状况分为营养状况良好组(n=85例)和营养状况不良组(n=51例)。分析新生儿缺氧缺血性脑病致病因素和影响新生儿缺氧缺血性脑病营养状况的危险因素。结果孕期疾病、分娩情况、新生儿常见并发症均为新生儿缺氧缺血性脑病的致病原因。孕期疾病包括孕期产科疾病和非产科疾病,孕期产科疾病主要有胎膜早破、妊娠高血压综合征、胎盘异常,分别占比为23.50%、27.20%、17.00%;非产科疾病以贫血为主,占比为11.03%;分娩情况以产程异常、脐带异常、羊水污染为主,占比为23.53%、36.76%、28.69%;新生儿常见并发症以黄疸、新生儿寒冷损伤综合征、肺部疾病为主,占比为23.53%、35.30%、16.18%。胎膜早破、妊娠高血压综合征、胎盘异常、乙型病毒性肝炎、贫血、产程异常、脐带异常、羊水污染、新生儿黄疸、新生儿寒冷损伤综合征、肺部疾病均为导致新生儿缺氧缺血性脑病患儿营养不良的原因,差异有统计学意义(P<0.05)。多因素logistic回归分析显示,胎膜早破、妊娠高血压综合征、胎盘异常、乙型病毒性肝炎、贫血、产程异常、脐带异常、羊水污染、新生儿黄疸、新生儿寒冷损伤综合征、肺部疾病是影响缺氧缺血性脑病新生儿营养不良的危险因素,差异有统计学意义(P<0.05)。结论上述影响因素是新生儿缺氧缺血性脑病患儿出现营养不良的危险因素,明确这些危险因素对预防新生儿缺氧缺血性脑病患儿出现营养不良状况具有一定指导意义。
Objective To analyze the risk factors affecting the nutritional status of neonates with hypoxic-ischemic encephalopathy(HIE)based on logistic regression.Methods A retrospective analysis was conducted on the clinical data of 136 neonates with HIE.According to their nutritional status,the neonates were divided into a good nutritional status group(n=85)and a poor nutritional status group(n=51).The pathogenic factors of neonatal HIE and the risk factors affecting the nutritional status of neonates with HIE were analyzed.Results Maternal diseases during pregnancy,delivery conditions,and common neonatal complications were all pathogenic causes of neonatal HIE.Maternal diseases during pregnancy included obstetric and non-obstetric diseases.Obstetric diseases mainly included premature rupture of membranes,pregnancy-induced hypertension syndrome,and placental abnormalities,accounting for 23.50%,27.20%,and 17.00%respectively;non-obstetric diseases were mainly anemia,accounting for 11.03%.Delivery conditions were dominated by abnormal labor process,umbilical cord abnormalities,and meconium-stained amniotic fluid,accounting for 23.53%,36.76%,and 28.69%respectively.Common neonatal complications mainly included jaundice,neonatal cold injury syndrome,and pulmonary diseases,accounting for 23.53%,35.30%,and 16.18%respectively.Premature rupture of membranes,pregnancy-induced hypertension syndrome,placental abnormalities,hepatitis B virus infection,anemia,abnormal labor process,umbilical cord abnormalities,meconium-stained amniotic fluid,neonatal jaundice,neonatal cold injury syndrome,and pulmonary diseases were all causes of malnutrition in neonates with HIE,with statistically significant differences(P<0.05).Multivariate logistic regression analysis showed that premature rupture of membranes,pregnancy-induced hypertension syndrome,placental abnormalities,hepatitis B virus infection,anemia,abnormal labor process,umbilical cord abnormalities,meconium-stained amniotic fluid,neonatal jaundice,neonatal cold injury syndrome,and pulmonary diseases were risk factors for malnutrition in neonates with HIE,with statistically significant differences(P<0.05).Conclusion The above influencing factors are risk factors for malnutrition in neonates with HIE.Identifying these risk factors is of great significance for preventing malnutrition in neonates with HIE.
作者
向梦佳
李嘉鑫
司凤霞
XIANG Mengjia;LI Jiaxin;SI Fengxia(Neonatal Ward,Henan Children’s Hospital&Zhengzhou Children’s Hospital,Zhengzhou Henan 450000,China)
出处
《河南医学高等专科学校学报》
2025年第4期374-377,共4页
Journal of Henan Medical College
基金
2019年度河南省医学科技攻关计划(联合共建)项目(LHGJ20191453)。
关键词
新生儿缺血缺氧性脑病
营养状况
危险因素
neonatal hypoxic-ischemic encephalopathy
nutritional status
risk factors
