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完善骨转移瘤多学科诊疗,重视骨相关事件的处理

Improve the multidisciplinary diagnosis and treatment of bone metastases and pay attention to handling of skeletal-related events
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摘要 随着肿瘤基础研究的深入、临床诊疗技术的不断提升,以及治疗理念的持续更新,肿瘤的治愈率和局部控制率均得到显著改善。当前,肿瘤治疗已由传统的单一治疗模式(如手术、放疗或化疗)逐步转变为包括药物治疗、靶向治疗、免疫治疗、精准医疗、手术干预及康复支持在内的多学科诊疗模式(multi-disciplinary treatment,MDT)。随着肿瘤MDT模式的广泛推广与不断优化,患者的生命风险显著降低,整体生存期实现了质的飞跃。本文就各种肿瘤骨相关事件(skeletal-related events,SREs)发生特点、骨转移瘤MDT系统的建立、SREs处理的国内现状和存在问题进行阐述,并提出改进意见。 With the in-depth basic tumor research,the continuous improvement of clinical diagnosis and treatment techniques,and the continuous update of treatment concepts,both the cure rate and local control rate of tumors have been significantly improved.At pres-ent,tumor treatment has gradually shifted from the traditional single treatment mode,such as surgery,radiotherapy or chemotherapy to a multi-disciplinary treatment(MDT)model involving drug therapy,targeted therapy,immunotherapy,precision medicine,surgical interven-tion and rehabilitation support.With the wide promotion and continuous optimization of the MDT model for tumors,the life risks of patients have been significantly reduced,and the overall survival period has achieved a qualitative leap.This article elaborates on the occurrence characteristics of skeletal related events(SREs)in various tumors,the establishment of the MDT system for bone metastases,the current do-mestic situation of handling skeletal-related events of bone metastases,existing problems,and improvement suggestions.
作者 伦登兴 胡永成 LUN Deng-xing;HU Yong-cheng(Department of Spinal Degeneration and Oncology,People's Hospital of Weifang City,Shandong Second Medical University,Weifang 261000,Shandong,China;Department of Bone and Soft Tissue Oncology,Tianjin Hospital,Tianjin 300000,China)
出处 《中国矫形外科杂志》 北大核心 2025年第14期1252-1257,共6页 Orthopedic Journal of China
关键词 肿瘤 骨转移 多学科诊疗模式 骨相关事件 tumor bone metastases multidisciplinary diagnosis and treatment model skeletal-related events
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