摘要
前哨淋巴结(SLN)是第1组参与肿瘤细胞转移扩散的淋巴结。SLN活检(SLNB)是指术中使用特异性示踪剂对SLN进行定位和活检,以评估淋巴结转移状态。它以侵袭性小、并发症少、诊断率高的特点在妇科恶性肿瘤中受到越来越多的重视和运用,也随之产生了一系列有待探索及解决的问题。文章介绍了常用的SLN示踪方法,并对外阴癌、子宫颈癌及子宫内膜癌中SLNB的研究进展和临床应用相关问题进行了讨论,为SLNB在妇科恶性肿瘤中的合理应用提供参考。
The sentinel lymph node(SLN)is the first group of lymph nodes involved in cancer metastasis.SLN biopsy(SLNB)refers to the positioning and biopsy of the SLNs in the operation using specific tracers to assess the status of lymph node metastasis.It has attracted increasing attention and has been applied in gynecological malignant tumors due to its less invasiveness,fewer complications,and high diagnostic rate.However,it also has produced a series of problems to be explored and solved.This review introduces the existing tracer methods,and discusses the indications of application and the clinical trials of SLNB in vulvar cancer,cervical cancer,and endometrial cancer in order to provide reference for the rational application of SLNB in gynecological malignant tumors.
作者
甘静雯
曹冬焱
Gan Jingwen;Cao Dongyan(National Clinical Research Center for Obstetric&Gynecologic Diseases,Department of Obstetrics and Gynecology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)
出处
《中华肿瘤杂志》
北大核心
2025年第8期689-695,共7页
Chinese Journal of Oncology
基金
北京协和医院中央高水平医院临床科研专项(2022-PUMCH-B082)。
关键词
外阴肿瘤
子宫颈肿瘤
子宫内膜肿瘤
前哨淋巴结活检
Vulvar neoplasms
Cervical neoplasms
Endometrial neoplasms
Sentinel lymph nodebiopsy
