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CT引导下经脂肪间隙胰腺穿刺切割活检术的临床应用

Clinical application of CT-guided pancreatic puncture-cutting biopsy via adipose tissue space
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摘要 目的评价CT引导下应用同轴引导针经脂肪间隙胰腺穿刺切割活检术的临床应用。方法回顾性分析2021年6月至2024年4月青岛大学附属医院平度院区CT引导下应用同轴引导针经脂肪间隙胰腺穿刺切割活检术患者30例,其中男20例,女10例,年龄(65.1±8.7)岁。病灶位于胰头7例、胰颈4例,胰体7例、胰尾10例,钩突2例,在CT引导下采用17 G同轴引导针经脂肪间隙建立穿刺通道,应用18 G带芯穿刺活检针取材,共实行胰腺穿刺切割活检术32次,其中包含再次活检术2例,取材结束后应用自制封堵剂明胶海绵颗粒-血凝酶混合液堵塞穿刺通道预防出血、胰漏及针道种植转移等并发症。结果30例患者共接受32次应用同轴引导针经脂肪间隙胰腺穿刺切割活检术,其中包含再次活检术2例。穿刺成功率100%(32/32)、取材成功率93.8%(30/32)、取材准确率93.8%(30/32)。所有病例无穿刺相关的严重并发症发生。结论CT引导下应用同轴引导针经脂肪间隙胰腺穿刺切割活检术是安全、准确、微创并值得推广应用的介入诊断技术。 Objective To evaluate the clinical application of CT-guided coaxial needle biopsy in pancreatic puncture-cutting biopsy via adipose tissue space.Methods The clinical data of 30 patients,who received CT-guided pancreatic coaxial needle biopsy via adipose tissue space at the Pingdu Hospital Area of Affiliated Hospital of Qingdao University of China from June 2021 to April 2024,were retrospectively analyzed.The patients included 20 males and 10 females with a mean age of(65.1±8.7)years.The lesions were located in the pancreatic head(n=7),pancreatic neck(n=4),pancreatic body(n=7),pancreatic tail(n=10)and uncinate process(n=2).Under CT guidance,a17 G co-axial guiding needle was inserted to establish a puncture pass through adipose tissue space,then an18 G biopsy needle was used to make tissue sampling.A total of 32 procedures of pancreatic puncture-cutting biopsy were performed,two of these patients received two times of biopsy.After sampling,a self-made blocking agent(a mixed liquid of gelatin sponge particles and snake venom hemagglutinin),was used to occlude the puncture channel so as to prevent complications such as bleeding,pancreatic leakage,needle tract implantation metastasis,etc.Results A total of 32 procedures of pancreatic puncture-cutting biopsy with coaxial guiding needle via adipose tissue space were performed,including two patients who received two times of biopsy.The success rate of puncturing was 100%(32/32),the success rate of sampling was 93.8%(30/32),and the accuracy of sampling was 93.8%(30/32).No serious puncture-related complications occurred in all patients.Conclusion CT-guided pancreatic coaxial needle biopsy via adipose tissue space is clinically safe,accurate in sampling and minimally-invasive.This interventional diagnostic technique is worth applying in clinical practice.
作者 韩景奇 吴则 王便 时艳 安玉芬 王彦华 HAN Jingqi;WU Ze;WANG Bian;SHI Yan;AN Yufen;WANG Yanhua(Department of Interventional Medicine,Pingdu Hospital Area of Affiliated Hospital of Qingdao University,Qingdao,Shandong Province 266700,China)
出处 《介入放射学杂志》 北大核心 2025年第7期746-751,共6页 Journal of Interventional Radiology
关键词 CT引导 同轴穿刺引导针 切割活检 封堵剂 明胶海绵颗粒-血凝酶 CT guidance coaxial puncture-guiding needle cutting biopsy blocking agent gelatin sponge particle-snake venom hemagglutinin
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