摘要
Objective:To investigate the efficacy of drug retention enema combined with deep hyperthermia in the treatment of radiation proctitis in patients with cervical cancer.Methods:A randomized controlled study was conducted,selecting 60 patients with radiation proctitis after cervical cancer,who were randomly divided into a control group and an experimental group of 30 cases each using the random number table method.Both groups of patients received conventional treatment.On this basis,the control group received drug retention enema.The experimental group was treated with deep hyperthermia in addition to the control group.Both groups were treated continuously for 1 month.Compare the clinical symptoms,quality of life,inflammatory markers,and effective treatment rate of the two groups after treatment.Results:Compared with the control group,the improvement in clinical symptoms after treatment in the experimental group was significantly better than that in the former(P<0.05);The quality of life score was significantly higher than that of the control group(P<0.05),and the inflammatory markers were significantly lower than those of the control group(P<0.05);the effective treatment rate was significantly higher than that of the control group(P<0.05).Conclusion:Drug retention enema combined with deep hyperthermia has a good therapeutic effect on radiation proctitis in cervical cancer patients undergoing radiotherapy,which can alleviate patient symptoms,improve quality of life,inhibit inflammatory response,and increase the effective treatment rate.
基金
Exploration of Radiotherapy Combined with Hyperthermia and Other Modalities to Reduce Radiation Enteritis in Gynecological Cancer Patients(Project No.2341ZF137).