摘要
目的 系统评价2019-2024年我国大学生HPV疫苗接种意愿及影响因素。方法 计算机检索中国知网(CNKI)、维普数据库(VIP)、万方数据库(Wanfang)、PubMed、Embase、Cochrane、Web of Science中与我国大学生HPV疫苗接种意愿率及影响因素相关的文献,检索时间从建库至2024年11月,使用Stata 15.0软件进行Meta分析。结果 本研究共纳入37篇文献,均为横断面研究,用随机效应模型合并效应量分析,显示2019-2024年我国大学生HPV疫苗接种意愿率为61.90%(95%CI:54.50%~69.20%),其中本科学历及以上(OR=2.45,95%CI:1.30~4.52)、有肿瘤家族史(OR=1.77,95%CI:1.37~2.48)、医学专业(OR=1.50,95%CI:1.30~1.74)、接受婚前性行为(OR=1.80,95%CI:1.46~2.23)、身边是否有人接种(OR=1.98,95%CI:1.48~2.64)、了解HPV(OR=1.96,95%CI:1.20~3.20)、了解HPV疫苗(OR=2.42,95%CI:1.51~3.87)、有过性经历(OR=2.51,95%CI:1.00~6.27)是我国大学生HPV疫苗接种意愿的影响因素。结论 我国大学生HPV疫苗接种意愿较高,但需加强对非医学专业及低认知学生的针对性宣教,重点提升学生对HPV感染风险和疫苗保护效果的认知。同时应优化疫苗可及性、推动同伴教育以提高接种率。此外,未来需开展男性接种及区域性研究,为全面推广提供数据支持。
Objective e To systematically evaluate the willingness of college students in China to receive the human papillomavirus(HPV)vaccine and identify the influencing factors from 2019 to 2024.Methods A computer-based search was conducted in the China National Knowledge Infrastructure,VIP Chinese Journal Service Platform,Wanfang Data Knowledge Service Platform,PubMed,Embase,Cochrane,and Web of Science for literature related to HPV vaccination willingness rates and its influencing factors among Chinese college students,with the search period spanning from database inception to November 2024.Meta-analysis was conducted using Stata 15.0 software.Results A total of 37 studies were included.A random-effects model combined with effect size analysis showed that the intention rate of HPV vaccination among college students in China from 2019 to 2024 was 61.90%[95%confidence interval(CD):54.50%-69.20%].Factors associated with increased willingness included having a bachelor's degree or higher odds ratio(OR=2.45,95%CI:1.30-4.52),a family history of cancer(OR=1.77,95%CI:1.37-2.48),being a medical major(OR=1.50,95%CI:1.30-1.74),acceptance of premarital sex(OR=1.80,95%CI:1.46-2.23),knowing someone had been vaccinated(OR=1.98,95%CI:1.48-2.64),knowledge of HPV(OR=1.96,95%CI:1.20-3.20),knowledge of the HPV vaccine(OR=2.42,95%CI:1.51-3.87),and having sexual experience(OR-2.51,95%CI:1.00-6.27)were the influential factors for HPV vaccination intention among college students in China.Conclusions The willingness of college students in China to receive the HPV vaccine was generally high.However,targeted education and publicityfor nonmedical majors and students with low cognition need to be strengthened,with a focus on enhancing students'awareness of the risk of HPV infection and the protective effect of the vaccine.Meanwhile,vaccine accessibility should be optimized,and peer education should be promoted to increase vaccination rates.In addition,male vaccination and regional studies should be conducted in the future to provide data to support comprehensive promotion.
作者
洪忠曦
安雪梅
黄琛
杨婷玉
罗咏源
熊西雅
HONG Zhongxi;AN Xuemei;HUANG Chen;YANG Tingyu;LUO Yongyuan;XIONG Xiya(Nursing College of Chengdu University of Traditional Chinese Medicine,Chengdu 610000,Sichuan,China;Deyang Iospital,Affiliated to Chengdu University of Traditional Chinese Medicine,Deyang 618000,Sichuan,China)
出处
《中国艾滋病性病》
北大核心
2025年第7期817-824,共8页
Chinese Journal of Aids & STD
基金
中西医协同慢病管理研究项目,编号:CXZH2024001。
关键词
人乳头瘤病毒疫苗
大学生
接种意愿
影响因素
HPV vaccine
college students
vaccination willingness
influencing factors
