摘要
目的探讨吸烟暴露对于重度原发性单症状夜间遗尿症临床疗效的影响。方法选取2018年1月至2022年1月于九江学院附属医院确诊为重度单症状性夜间遗尿症的120例患儿作为研究对象,根据是否干预吸烟暴露分为治疗组与对照组,每组60例。对照组未干预吸烟暴露,治疗组干预吸烟暴露,所有患儿均口服醋酸去氨加压素。比较两组临床疗效、复发情况及睡眠深度、遗尿次数、遗尿量症状积分。结果治疗组总缓解率高于对照组,差异有统计学意义(P<0.05)。治疗组复发率低于对照组,差异有统计学意义(P<0.05)。治疗后,两组睡眠深度症状积分、遗尿次数症状积分、遗尿量症状积分均低于治疗前,且治疗组低于对照组,差异有统计学意义(P<0.05)。结论吸烟暴露对儿童原发性单症状夜间遗尿症的治疗效果显著,及时干预吸烟暴露可有效改善睡眠深度,减少遗尿次数及遗尿量,可降低患儿复发率。
Objective To explore the influence of smoking exposure on the clinical efficacy of severe primary monosymptomatic nocturnal enuresis.Methods A total of 120 children diagnosed with severe monosymptomatic nocturnal enuresis in the Jiujiang University Affiliated Hospital from January 2018 to January 2022 were selected as the research subjects,they were divided into the treatment group and the control group according to whether smoking exposure was intervened,with 60 cases in each group.The control group did not intervene smoking exposure,while the treatment group intervened smoking exposure,all children were orally administered desmopressin acetate.The clinical efficacy,recurrence rate,and symptom scores of sleep depth,enuresis frequency,and enuresis volume were compared between the two groups.Results The total remission rate in the treatment group was higher than that in the control group,and the difference was statistically significant(P<0.05).The recurrence rate in the treatment group was lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the symptom scores of sleep depth,enuresis frequency,and enuresis volume of the two groups were lower than those before treatment,and the treatment group was lower than the control group,and the differences were statistically significant(P<0.05).Conclusion Smoking exposure has a significant impact on the treatment effect of primary monosymptomatic nocturnal enuresis in children,timely intervention of smoking exposure can effectively improve sleep depth,reduce enuresis frequency and volume,and lower the recurrence rate of children.
作者
陶瑾
戴洪银
幸伶俐
胡琦
邓新喜
TAO Jin;DAI Hongyin;XING Lingli;HU Qi;DENG Xinxi(Department of Pediatrics,Jiujiang University Affiliated Hospital,Jiujiang,Jiangxi,332000,China;Department of Urology,Jiujiang No.1 People's Hospital,Jiujiang,Jiangxi,332000,China)
出处
《当代医学》
2025年第4期146-149,共4页
Contemporary Medicine
基金
九江市科技计划项目(S2021ZDYFN146)。
