摘要
下肢动脉硬化闭塞症(ASO)是常见的外周动脉疾病,全球发病率逐年上升。动脉钙化作为ASO的重要病理改变,在其发病机制、诊断评估、治疗策略和预后判断中均具有重要意义。近年来,随着影像学和生物标志物检测技术的不断进步,动脉钙化的定量评估和临床研究不断深入,为个体化诊疗提供了新思路。本综述从动脉钙化的病理生理机制出发,系统梳理其检测方法、对腔内治疗的影响以及在预后评估中的应用进展,旨在为ASO患者的精准治疗提供理论依据和实践参考。
Lower extremity atherosclerotic occlusive disease(ASO)is a common peripheral arterial disease with a steadily increasing global incidence.As a key pathological change in ASO,arterial calcification plays a crucial role in its pathogenesis,diagnostic evaluation,treatment strategies,and prognosis.In recent years,with the continuous advancement of imaging and biomarker detection technologies,quantitative assessment and clinical research on arterial calcification have deepened,providing new perspectives for individualized diagnosis and treatment.This review begins with the pathophysiological mechanisms of arterial calcification and systematically summarizes current detection methods,its impact on endovascular therapy,and recent progress in prognostic evaluation,aiming to provide theoretical support and practical reference for precision treatment of ASO patients.
作者
刘一博
慈红波
LIU Yibo;CI Hongbo(Graduate School of Xinjiang Medical University,Urumqi 830000,China;Department of Vascular Surgery,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830001,China)
出处
《中国普通外科杂志》
北大核心
2025年第6期1275-1281,共7页
China Journal of General Surgery
基金
新疆维吾尔自治区自然科学基金资助项目(2024D01C106)。
关键词
闭塞性动脉硬化
下肢
血管钙化
综述
Arteriosclerosis Obliterans
Lower Extremity
Vascular Calcification
Review
