摘要
高度近视是我国常见病之一,一般认为其发病与遗传有关。但国内尚未见到从遗传角度进行系统的家系分析,因此对我国人中高度近视的遗传规律还不够了解,国外偶有家系分析报告,但一般仅限于个别家庭,缺乏大组分析,因此意见也不一致。为此,我们从1972-1978年对61个高度近视病员的家庭进行了调查,并从遗传学角度作了统计分析。现将结果报道如下。
We investigated 404 relatives of 61 patients suffering from high myopia during 1972-1978.1.In 4 families both parents and all children are highly myopia.2.Both parents are apparently normal.Of their children high myopia accounts for 21.3%(Weinberg’s correction)or 22.2%(Lenz’s correction).3.Of the 35 families,each with one parent highly myopia and the other apparently normal,7 families have highly myopia children accoumting for 20%of the total,which corresponds to the frequency of heterozygotes in the population.(The frequency of high myopia is 1-2%,corresponding to a frequency of 18-24%heterozygotes in the population.)These findings suggest that high myopia is generally inherited as an autosomal recessive.
出处
《科学通报》
1979年第18期860-864,共5页
Chinese Science Bulletin
