摘要
糖尿病足溃疡(DFU)是糖尿病严重并发症之一,易导致截肢,严重影响患者生活质量。DFU病因复杂,涉及血管病变、神经病变和感染等,西医治疗手段有限。中医将其归为“脱疽”,四妙勇安汤作为常用方剂,在临床中具有改善血流、修复神经、控制感染及促进愈合等作用。本文综述了DFU的中医病机及四妙勇安汤的临床与实验研究进展,为其治疗提供科学依据。
Diabetic foot ulcer(DFU)is one of the severe complications of diabetes mellitus,which often leads to amputation and seriously impairs patients'quality of life.It has complex etiology,involving vascular disease,neuropathy,and infection,etc.,and western medical treatment options are limited.In traditional Chinese medicine(TCM),DFU is classified as"tuoju"(gangrene of the extremities).Simiao Yong'an Decoction,a commonly used formula,has demonstrated clinical effects in improving blood flow,repairing nerves,controlling infection,and promoting wound healing.This article reviewed the TCM pathogenesis of DFU and the clinical and experimental research progress of Simiao Yong'an Decoction,aiming to provide a scientific basis for its treatment.
作者
李沛璘
陈笑吟
鲍新坤
LI Peilin;CHEN Xiaoyin;BAO Xinkun(Hubei University of Chinese Medicine,Wuhan,Hubei,430000;Department of Proctology,Hubei Provincial Hospital of Traditional Chinese Medicine,Wuhan,Hubei,430000)
出处
《实用临床医药杂志》
2025年第13期132-136,共5页
Journal of Clinical Medicine in Practice
基金
湖北省卫生健康委员会中医药科研项目(ZY2021Q034)。
关键词
糖尿病足溃疡
四妙勇安汤
中医治疗
周围神经病变
血管病变
创面愈合
炎症调控
脱疽
diabetic foot ulcer
Simiao Yong'an Decoction
treatment by traditional Chinese medicine
peripheral neuropathy
vascular disease
wound healing
inflammation regulation
"tuoju"
