摘要
目的探讨甲状腺癌合并原发性甲状旁腺功能亢进症(primary hyperparathyroidism,PHPT)患者的外科治疗策略。方法回顾性分析2016年1月至2022年1月于首都医科大学附属北京友谊医院行手术治疗的甲状腺癌患者的病历资料,其中合并PHPT患者22例纳入研究组,按照1∶2比例从同期甲状腺癌患者中随机抽取44例纳入对照组。比较两组患者的手术时间、术中出血量、住院时间、并发症发生情况。结果研究组患者的手术时间显著长于对照组(P<0.01)。两组患者的术中出血量、住院时间比较差异均无统计学意义(P>0.05)。研究组患者发生暂时性低钙血症5例,对照组患者发生暂时性低钙血症12例,切口感染1例,两组患者的术后并发症发生率比较差异无统计学意义(P>0.05)。结论甲状腺癌合并PHPT增加治疗复杂性,通过充分的术前诊断及合理的外科治疗策略,可有效降低二次手术及术后并发症风险,改善患者预后。
Objective To explore the surgical treatment strategy for patients with thyroid cancer complicated with primary hyperparathyroidism(PHPT).Methods A retrospective analysis was conducted on the case data of thyroid cancer patients who underwent surgical treatment at Beijing Friendship Hospital,Capital Medical University from January 2016 to January 2022.Among them,22 patients with PHPT were included in study group,and 44 patients were randomly selected from thyroid cancer patients during the same period at a ratio of 1∶2 and included in control group.The operation time,intraoperative blood loss,hospital stay and occurrence of complications of two groups of patients were compared.Results The operation time of patients in study group was significantly longer than that in control group(P<0.01).There was no statistically significant difference in intraoperative blood loss and hospital stay between two groups of patients(P>0.05).There were 5 cases of temporary hypocalcemia in study group,12 cases of temporary hypocalcemia and 1 case of incision infection in control group.There was no statistically significant difference in incidence of postoperative complications between two groups of patients(P>0.05).Conclusion Thyroid cancer complicated with PHPT increases the complexity of treatment.Through adequate preoperative diagnosis and reasonable surgical treatment strategies,the risks of secondary surgery and postoperative complications can be effectively reduced,and the prognosis of patients can be improved.
作者
杜安然
安磊
滕长胜
葛智成
张忠涛
丁国乾
DU Anran;AN Lei;TENG Changsheng;GE Zhicheng;ZHANG Zhongtao;DING Guoqian(Second School of Clinical Medicine,Capital Medical University,Beijing 100050,China;Department of General Surgery,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)
出处
《中国现代医生》
2025年第22期31-35,共5页
China Modern Doctor
