摘要
目的探讨中上臂围(mid-upper arm circumference,MUAC)与中老年2型糖尿病(type 2 diabetes mellitus,T2DM)肌少症患者的关联。方法选取2022年3月至2024年10月南京鼓楼医院集团宿迁医院收治的中老年T2DM患者402例,其中单纯糖尿病患者308例,纳入非肌少症组,合并肌少症患者94例,纳入肌少症组。采用多因素Logistic回归分析确定MUAC与中老年T2DM患者合并肌少症的关联。利用受试者操作特征曲线评估MUAC对中老年T2DM患者合并肌少症的预测能力。结果两组患者的年龄、体质量指数、MUAC、甘油三酯、直接胆红素、丙氨酸转氨酶、天冬氨酸转氨酶、四肢骨骼肌质量、四肢骨骼肌质量指数、握力和6m步速比较差异均有统计学意义(P<0.05)。多因素Logistic回归分析结果显示MUAC较小、年龄增大均是中老年T2DM患者合并肌少症的危险因素(P<0.05)。MUAC诊断中老年T2DM患者合并肌少症的最佳截断值:男性为27.90cm,女性为26.95cm。结论MUAC与中老年T2DM患者合并肌少症相关,可用于早期识别和诊断中老年T2DM合并肌少症。
Objective To explore the association between mid-upper arm circumference(MUAC)and sarcopenia in middle-aged and elderly patients with type 2 diabetes mellitus(T2DM).Methods A total of 402 middle-aged and elderly patients with T2DM admitted to Nanjing Drum Tower Hospital Group Suqian Hospital from March 2022 to October 2024 were selected.Among them,308 patients with simple diabetes mellitus were included in non-sarcopenia group,and 94 patients with combined sarcopenia were included in sarcopenia group.Multivariate Logistic regression analysis was used to determine the association between MUAC and sarcopenia in middle-aged and elderly patients with T2DM.The predictive ability of MUAC for sarcopenia in middle-aged and elderly patients with T2DM was evaluated by using the receiver operating characteristic curve.Results There were statistically significant differences in age,body mass index,MUAC,triglycerides,direct bilirubin,alanine aminotransferase,aspartate aminotransferase,appendicular skeletal muscle mass,appendicular skeletal muscle mass index,grip strength and 6-meter walking speed between two groups of patients(P<0.05).The results of multivariate Logistic regression showed that a smaller MUAC and increased age were both risk factors for sarcopenia in middle-aged and elderly patients with T2DM(P<0.05).The optimal cutoff value of MUAC for diagnosing sarcopenia in middle-aged and elderly patients with T2DM:27.90cm for males and 26.95cm for females.Conclusion MUAC is associated with sarcopenia in middle-aged and elderly patients with T2DM and can be used for the early identification and diagnosis of middle-aged and elderly T2DM patients with sarcopenia.
作者
李茜
叶梦
苏芳
王文
吴研哲
吴利
朱红
LI Qian;YE Meng;SU Fang;WANG Wen;WU Yanzhe;WU Li;ZHU Hong(Department of Clinical Nutrition,the Afffliated Suqian Hospital of Xuzhou Medical University,Nanjing Drum Tower Hospital Group Suqian Hospital,Suqian 223800,Jiangsu,China;Department of Endocrinology,the Afffliated Suqian Hospital of Xuzhou Medical University,Nanjing Drum Tower Hospital Group Suqian Hospital,Suqian 223800,Jiangsu,China;Department of Clinical Medicine,Chengde Medical University,Chengde 067050,Hebei,China)
出处
《中国现代医生》
2025年第22期16-20,25,共6页
China Modern Doctor
基金
江苏省宿迁市指导性科技计划项目(Z2023107)。
关键词
2型糖尿病
肌少症
中上臂围
中老年
Type 2 diabetes mellitus
Sarcopenia
Mid-upper arm circumference
Middle-aged and elderly
