摘要
目的研究临床微生物检验工作中应用细菌耐药性检测的可行性。方法对2022年1月至2023年12月期间本院收集的2953例致病菌样本进行了细菌耐药性监测,通过临床微生物检验了解菌株分布并分析耐药性结果。结果在2953例致病菌中,大肠埃希菌检出率最高(16.76%),其次是产气肠杆菌(14.49%)、肺炎克雷伯菌(12.43%)。耐药性监测结果显示,与大肠埃希菌、肺炎克雷伯菌相比,产气肠杆菌对头孢呋辛和氨曲南的耐药性最高(P<0.05),与产气肠杆菌、肺炎克雷伯菌相比,大肠埃希菌对环丙沙星的耐药性最高(P<0.05)。结论细菌耐药性监测在临床微生物检验中不仅能提高细菌检出率,还能提供详细的耐药性变化信息。
Objective To investigate the feasibility of using bacterial resistance monitoring in clinical microbiological testing.Methods Bacterial resistance monitoring was conducted on 2953 pathogenic bacteria samples collected by our hospital from January 2022 to December 2023.The distribution of bacterial strains was understood through clinical microbiological testing,and the results of drug resistance were analyzed.Results Among 2953 cases of pathogenic bacteria,Escherichia coli had the highest detection rate(16.76%),followed by Escherichia coli(14.49%)and Klebsiella pneumoniae(12.43%).The results of drug resistance monitoring showed that compared with Escherichia coli and Klebsiella pneumoniae,Escherichia coli had the highest resistance to cefuroxime and azuron(P<0.05).Compared with Escherichia coli and Klebsiella pneumoniae,Escherichia coli had the highest resistance to ciprofloxacin(P<0.05).Conclusions Bacterial resistance monitoring can not only improve the detection rate of bacteria in clinical microbiological testing,but also provide detailed information on changes in drug resistance.
作者
张砾
ZHANG Li(Department of Laboratory,Wuhan Iron and Steel(Group)Company Second Staff Hospital,Wuhan,Hubei 430085,China)
出处
《中国医药指南》
2025年第20期96-98,共3页
Guide of China Medicine
关键词
微生物检验
细菌
耐药性监测
临床
Microbial testing
Bacteria
Drug resistance monitoring
Clinical
