摘要
目的探讨液体复苏联合连续性静脉-静脉血液滤过(CVVH)在重症感染性休克患者中的应用效果。方法选取苏州市立医院2022年1月至2024年12月150例重症感染性休克患者,用随机数字表法分为对照组(75例,液体复苏治疗)和观察组(75例,液体复苏+CVVH联合治疗)。对比两组患者的血气分析指标、机械通气时间、24 h输液量、ICU住院时间及预后情况。结果治疗后,两组患者的各项血气分析指标水平均较治疗前有所改善,且观察组各时间点的改善情况均更优(P<0.05)。治疗28 d后的MODS发生率、并发症发生率及病死率比较,观察组更低(P<0.05)。结论液体复苏联合CVVH治疗感染性休克患者能够更有效地改善血气分析指标,缩短机械通气时间和ICU住院时间,减少MODS、并发症发生风险及病死率。
Objective To explore the application effect of fluid resuscitation combined with continuous veno-venous hemofiltration(CVVH)in patients with severe septic shock.Methods A total of 150 patients with severe septic shock from Suzhou Municipal Hospital from from January 2022 to December 2024.were selected.The patients were divided into control group(75 cases,liquid resuscitation treatment)and observation group(75 cases,liquid resuscitation+CVVH combined treatment)by random number table.Blood gas analysis indexes,mechanical ventilation time,24 hours infusion volume,ICU stay and prognosis were compared between the two groups.Results After treatment,the levels of blood gas analysis indexes in both groups were improved compared with those before treatment,and the improvement at each time point in the observation group was significantly better(P<0.05).After 28 days of treatment,the incidence of MODS,complication rate and mortality were significantly lower in the observation group(P<0.05).Conclusions Liquid resuscitation combined with CVVH can effectively improve blood gas analysis indexes,shorten mechanical ventilation time and ICU stay,and reduce the risk of MODS,complications and mortality in septic shock patients.
作者
贾娜
许彬
JIA Na;XU Bin(Department of Emergency and Critical Care Medicine,Gusu School Nanjing Medical University,Suzhou Municipal Hospital/The Affiliated Suzhou Hospital of Nanjing Medical University,Suzhou,Jiangsu 215002,China)
出处
《中国医药指南》
2025年第21期132-134,共3页
Guide of China Medicine
