摘要
Biodegradable zinc(Zn)and its alloys have rapidly emerged as a promising alternative for implants with medium to high loadbearing requirements due to their superior strength and ductility compared to Mg alloys in the past decade[1].Furthermore,the in vivo degradation rates of Zn-based devices more closely match the tissue healing periods(3-6 months for vascular healing[2],2-3 months for bone healing[3]).Recent studies have demonstrated the ability of Zn alloys to promote osteogenesis and modulate immune responses[3,4].These exciting findings have accelerated the translational research of Zn alloys,with clinical studies initiated to evaluate the safety and efficacy of biodegradable Zn alloy devices such as a maxillofacial internal fixation system,interference screws,and a resorbable Zn alloy drugeluting coronary artery stent.
