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ERCP治疗胆管结石伴胆管炎患者的疗效及复发情况

Efficacy and Recurrence of ERCP in the Treatment of Patients with Bile Duct Stones and Cholangitis
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摘要 目的探讨内镜逆行性胰胆管造影术(endoscopic retrograde cholangiopancreatography,ERCP)治疗胆管结石伴胆管炎患者的效果和复发情况。方法目的选取2021年3月—2024年4月盱眙县人民医院收治的150例胆管结石伴胆管炎患者为研究对象。根据术式不同分为75例参照组、75例观察组。参照组选择胆总管切开取石术,观察组选择ERCP。比较两组临床疗效、围术期指标、复发情况、并发症发生情况。结果观察组治疗总有效率高于参照组,差异有统计学意义(P<0.05)。观察组手术时间、术中出血量、肛门排气时间、住院时间分别为(74.25±9.52)min、(52.36±6.45)mL、(15.25±2.45)h、(7.52±1.25)d,优于参照组的(82.45±12.36)min、(79.42±10.25)mL、(20.74±4.25)h、(10.45±2.36)d,差异均有统计学意义(t=4.552,19.351,9.692,9.501;P均<0.05)。观察组复发率及并发症总发生率均低于参照组,但差异均无统计学意义(P均>0.05)。结论胆管结石伴胆管炎患者治疗中应用ERCP疗效显著且显示出手术用时短,有包括但不限于安全、预后理想等多重优势,具体表现为术后功能指标快速恢复,且不会明显增加术后复发及并发症发生风险。 Objective To investigate the effect and recurrence of endoscopic retrograde cholangiopancreatography(ERCP)in the treatment of patients with bile duct stones and cholangitis.Methods A total of 150 cases of patients with bile duct stones and cholangitis admitted to Xuyi County People′s Hospital from March 2021 to April 2024 were purposefully selected as the study subjects.According to different surgical methods,they were divided into 75 cases of reference group and 75 cases of observation group.The reference group chose choledocholithotomy,and the observa-tion group chose ERCP.The clinical efficacy,perioperative indexes,recurrence and complications were compared be-tween the two groups.Results The total effective rate of treatment in the observation group was higher than that in the reference group,and the difference was statistically significant(P<0.05).The operation time,intraoperative blood loss,anal exhaust time and hospitalization time of the observation group were(74.25±9.52)min,(52.36±6.45)mL,(15.25±2.45)h and(7.52±1.25)d,respectively,which were better than those of the reference group(82.45±12.36)min,(79.42±10.25)mL,(20.74±4.25)h and(10.45±2.36)d,and the differences were statistically significant(t=4.552,19.351,9.692,9.501;all P<0.05).The recurrence rate and total incidence of complications in the observation group were lower than those in the reference group,but the differences were not statistically significant(all P<0.05).Con-clusion The application of ERCP in the treatment of patients with bile duct stones and cholangitis has a significant ef-fect and shows a short operation time,including but not limited to multiple advantages such as safety and ideal progno-sis.The specific performance is the rapid recovery of postoperative functional indicators,and will not significantly in-crease the risk of postoperative recurrence and complications.
作者 张永琪 ZHANG Yongqi(Department of Gastroenterology,Xuyi County People′s Hospital,Xuyi 211700,Jiangsu,China)
出处 《系统医学》 2025年第12期95-98,共4页 Systems Medicine
关键词 胆管结石 胆管炎 胆总管切开取石术 围术期指标 复发情况 Choledocholithiasis Cholangitis Choledochotomy and lithotripsy Perioperative indicators Recurrence
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