摘要
胃癌是全球高发的消化道恶性肿瘤,影像学早期诊断困难,病理诊断存在空间异质性及侵入性局限。影像组学通过高通量提取影像特征并量化分析,为肿瘤异质性可视化及生物学行为解析提供了无创、可重复的新方法。当前研究集中于影像组学在胃癌病理分型(如Lauren分型)、分子标志物预测、TNM分期及疗效评估中的应用,其模型在临床验证中展现出高敏感性与特异性,但仍面临标准化不足、样本量小及外部验证缺乏等挑战。目前尚缺乏影像组学对胃癌的精准诊断和疗效监测中的系统性归纳。因此,本文系统综述影像组学在胃癌诊疗中的研究进展,旨在为个体化精准治疗提供新思路,推动临床转化。
Gastric cancer is a high-incidence gastrointestinal malignancy in the world,and early diagnosis is difficult and the prognosis is poor.The accuracy of traditional imaging diagnosis is low,while pathological diagnosis has spatial heterogeneity and invasive limitations.Radiomics provides a non-invasive and reproducible new method for visualizing tumor heterogeneity and analyzing biological behaviors through high-throughput extraction and quantitative analysis of image features.Current research focuses on the application of radiomics in gastric cancer pathological classification(e.g.,Lauren classification),molecular marker prediction,TNM staging and efficacy evaluation,and its models have shown high sensitivity and specificity in clinical validation,but still face challenges such as insufficient standardization,small sample size and lack of external validation.This article systematically reviews the research progress of radiomics in the diagnosis and treatment of gastric cancer,aiming to provide new ideas for individualized precision treatment and promote clinical translation.
作者
廖蔓芸
华丽
陈绍俊
LIAO Manyun;HUA Li;CHEN Shaojun(Department of Oncology,the Fourth Affiliated Hospital of Guangxi Medical University,Liuzhou 545005,China)
出处
《磁共振成像》
北大核心
2025年第7期177-184,共8页
Chinese Journal of Magnetic Resonance Imaging
基金
柳州市胃癌基础和临床研究重点实验室项目。
关键词
影像组学
胃癌
磁共振成像
诊断
疗效
radiomics
gastric cancer
magnetic resonance imaging
diagnosis
efficacy
