摘要
急性高原反应(acute mountain sickness,AMS)是高原病中最常见的类型,随着旅游业的蓬勃发展、军事任务的频繁执行以及户外探险活动的日益普及,进入高原地区的人群数量连续逐年增加,早期诊断AMS对预防疾病进展为严重甚至危及生命的阶段至关重要。近年来,神经影像学领域取得了显著的进展,为AMS的临床诊断及病理机制的深入剖析开辟了全新视野。本文就多模态MRI在脑容量、脑组织微结构损伤、脑血流灌注的最新应用进展总结,为AMS的诊断及机制探索提供新的新的视角。
Acute mountain sickness(AMS)is the most common form of altitude illness.With the booming tourism industry,frequent military operations,and increasing popularity of outdoor adventures,the number of individuals entering high-altitude regions has risen steadily,making early AMS diagnosis critical to preventing progression to severe,life-threatening stages.Recent advances in neuroimaging have opened new avenues for clinical diagnosis and in-depth analysis of AMS pathophysiology.This article reviews the latest applications of multimodal MRI in assessing brain volume,microstructural damage,and cerebral blood flow perfusion,offering novel perspectives for AMS diagnosis and mechanistic exploration.
作者
郭雅
鲍海华
陶涛
温生宝
白艳玲
贺春兰
GUO Ya;BAO Haihua;TAO Tao;WEN Shengbao;BAI Yanling;HE Chunlan(School of Clinical Medicine,Qinghai University,Xining 810000,China;Department of Medical Imaging,Affiliated Hospital of Qinghai University,Xining 810000,China;Department of Laboratory Medicine,Affiliated Hospital of Qinghai University,Xining 810000,China;Department of Urology,Affiliated Hospital of Qinghai University,Xining 810000,China)
出处
《磁共振成像》
北大核心
2025年第7期135-139,146,共6页
Chinese Journal of Magnetic Resonance Imaging
基金
国家临床重点专科建设项目(编号:青海省卫生健康委员会办公室〔2024〕90号)。
关键词
急性高原反应
磁共振成像
脑容量
脑血流灌注
acute mountain sickness
magnetic resonance imaging
brain volume
cerebral perfusion
