摘要
自闭症谱系障碍(autism spectrum disorder,ASD)以社交障碍和重复、受限行为为核心症状,全球患病率持续上升。但由于ASD的脑机制尚不明确,其早期诊断、早期干预受到限制。神经影像学是探索ASD脑机制重要的研究手段,目前少有综述去概述这一研究进展。本文主要总结了ASD神经影像学的改变以及其背后的临床意义和脑机制,以期为后续影像学的研究以及脑机制的探索提供帮助。
Autism spectrum disorder(ASD)is characterized by core symptoms of social communication deficits and restricted,repetitive behaviors,with its global prevalence steadily increasing.However,the brain mechanism of ASD is still unclear,and its early diagnosis and early intervention are limited.Neuroimaging is an important research tool for exploring the brain mechanisms of ASD,but few reviews have summarized this research progress.This review primarily summarizes the neuroimaging alterations in ASD,their clinical significance and associated brain mechanisms,in order to support subsequent imaging studies and advance the exploration of brain mechanisms.
作者
张淑婷
韩超
徐靖尧
陈新晖
李舟
王梅云
ZHANG Shuting;HAN Chao;XU Jingyao;CHEN Xinhui;LI Zhou;WANG Meiyun(Department of Radiology,Zhengzhou University People's Hospital,Zhengzhou 450003,China;Department of Radiology,Henan Provincial People's Hospital,Zhengzhou 450003,China;Department of Radiology,General Hospital of Pingmei Shenma Medical Group,Pingdingshan 467000,China;Department of Neurology,General Hospital of Pingmei Shenma Medical Group,Pingdingshan 467000,China;Henan Provincial Engineering Research Center for Magnetic Resonance-guided Focused Ultrasound(Magnetic Wave Knife)Treatment,Zhengzhou 450003,China;Henan Key Laboratory for Medical Imaging of Neurological Diseases,Zhengzhou 450003,China;Henan Provincial Engineering Technology Research Center for Medical Imaging Diagnosis and Treatment,Zhengzhou 450003,China)
出处
《磁共振成像》
北大核心
2025年第7期91-96,128,共7页
Chinese Journal of Magnetic Resonance Imaging
基金
国家重点研发计划项目(编号:2023YFC2414200)。
关键词
自闭症谱系障碍
神经影像学
静息态磁共振成像
脑机制
磁共振成像
autism spectrum disorder
neuroimaging
resting-state functional magnetic resonance imaging
brain mechanisms
magnetic resonance imaging
