摘要
Planar chiral cyclophanes are a type of structurally intriguing organic molecules,which have found increasingly applications in the field of biologically active compounds,asymmetric catalysis,and optically pure materials.As such,significant efforts in the development of new methods to build up enantioenriched cyclophanes in a precise manner have attracted increased attention in recent years.Among the plethora of reported synthetic strategies,catalytic enantioselective method has emerged as one of the most straightforward and efficient ways to deliver optically pure planar chiral cyclophanes.In this review,the recent progress in catalytic enantioselective reactions for the synthesis of planar chiral cyclophanes will be discussed,which would stimulate the research interest of chemists for the discovery of novel asymmetric strategies for the preparation of valuable and previously difficult-to-access chiral molecules.
基金
financial support provided by Huanghuai University and Hangzhou Medical College.
