摘要
糖尿病下肢动脉疾病(diabetic lower extremity arterial disease,DLEAD)具有低诊断、低知晓、低治疗、高致残及高致死的现状。临床缺乏完善的防治手段及综合技术体系,使其成为现阶段临床糖尿病防控的瓶颈问题。中医治疗DLEAD具有辨证论治、整体调节的优势,但缺乏全程病机认识及统一规范的证候标准;中药治疗该疾病具有多靶点多通路网络效应,但优势环节不明确;中医药可延缓DLEAD发生发展,但疗效评价体系不完善,缺乏高质量循证医学证据和临床共识指南。因此,基于中医“治未病”思想,本研究聚焦DLEAD的防控难题,构建了集预防、诊疗、机制与应用于一体的中西医协同防治DLEAD技术体系,以提升DLEAD临床防控效果,开创中西医协同在慢病领域的新范式。
Diabetic lower extremity arterial disease(DLEAD)is characterized by a low rate of diagnosis,low awareness,low treatment rate,high disability rate,and high mortality.Due to a lack of comprehensive prevention and treatment strategies or an integrated technological system,DLEAD has become a bottleneck in the prevention and control of diabetes mellitus at present.Traditional Chinese medicine(TCM)treatment of DLEAD offers the advantages of syndrome differentiation,evidence-based treatment,and holistic regulation.However,it lacks a comprehensive understanding of the through-course pathogenesis and unified standardized syndrome criteria.TCM treatment of DLEAD exerts multi-target and multi-pathway network effects,but the advantageous links are still not fully understood.TCM treatments can delay the onset and development of DLEAD,but the efficacy evaluation system remains incomplete.Furthermore,there is a lack of high-quality evidence-based medical evidence and clinical consensus and guidelines.Therefore,based on the idea of zhi wei bing,or treating the disease before it develops,in Chinese medicine,and focusing on the prevention and control of DLEAD,we have constructed a synergistic technical system that integrates traditional Chinese and Western medicine for the prevention and control of DLEAD.This system integrates prevention,diagnosis,treatment,mechanisms,and applications,so as to enhance the clinical effects of DLEAD prevention and control,and to create a new paradigm for collaborative traditional Chinese medicine and western medicine in the field of chronic disease management.
作者
高泓
谢红艳
梁清芝
谢春光
GAO Hong;XIE Hongyan;LIANG Qingzhi;XIE Chunguang(TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,China;Department of Endocrinology,Hospital of Chengdu University of Traditional Chinese Medicine Chengdu,610072,China)
出处
《四川大学学报(医学版)》
北大核心
2025年第3期633-639,共7页
Journal of Sichuan University(Medical Sciences)
基金
国家中医药管理局中西医协同慢病管理项目(No.CXZH2024094)
国家中医药传承创新团队项目(No.ZYYCXTD-C-202209)
委校联合创新基金-循证专项(No.WXLH202401001)
四川省中医药科技产业创新团队专项(No.2022C012)资助。
关键词
糖尿病下肢动脉疾病
中西医结合
治未病
Diabetic lower extremity arterial disease
Integration of traditional Chinese medicine and western medicine
Preventive treatment of disease
