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僵人综合征的麻醉管理

Anesthesia in stiff‑person syndrome
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摘要 僵人综合征(SPS)是神经内科的罕见疾病,临床麻醉经验较少。目前尚无文献明确可安全用于SPS患者的麻醉药物。既往麻醉经验提示,肌松药和吸入麻醉药可能造成SPS患者术后肌力恢复障碍,可能与SPS治疗药物巴氯芬有关。文章综述了SPS的临床特点、主要病理机制和既往麻醉经验,通过总结现有临床经验,旨在为SPS患者的麻醉管理提供指导,改善这类特殊患者的预后。 Stiff‑person syndrome(SPS)is a rare neurological disease that is absence of clinical anesthesia protocol.No literature provides a definite effective and safe anesthetic for SPS.Previous anesthesia experience indicated that muscle relaxation drugs and inhaled anesthetics caused postoperative muscle strength recovery disorders in patients with SPS,probably related to the SPS treatment drug Baclofen.This review summarizes the clinical characteristics,main pathological mechanisms and previously anesthesia experiences of SPS.
作者 段庆芳 金笛 尹橙 田甜 苗芳芳 王天龙 Duan Qingfang;Jin Di;Yin Cheng;Tian Tian;Miao Fangfang;Wang Tianlong(Department of Anesthesiology,Xuanwu Hospital of Capital Medical University,Beijing 100053,China)
出处 《国际麻醉学与复苏杂志》 2025年第6期643-646,共4页 International Journal of Anesthesiology and Resuscitation
关键词 僵人综合征 麻醉管理 肌松药 吸入麻醉药 Stiff‑person syndrome Anesthetic management Muscle relaxant Inhalation anesthetic
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