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冰硼痔疮栓对痔病患者肛门疼痛及生活质量影响的临床研究

Clinical study on the effect of bingboron hemorrhoid suppository on anal pain and quality of life in hemorrhoid patients
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摘要 目的探讨冰硼痔疮栓对痔病患者肛门疼痛及生活质量的影响。方法回顾性分析2019年12月~2021年1月于四川省第二中医医院肛肠科收治的110例痔病患者资料。根据治疗方法将患者分为两组,其中观察组56例进行冰硼痔疮栓治疗,对照组54例进行马应龙麝香痔疮栓治疗。对比两组治疗前后不同时间点的视觉模拟疼痛(Visual Analogue Scale,VAS)评分、生活质量量表(Generic Quality of Life Inventory-74,GQOLI-74)评分和疾病缓解率,并统计比较两组住院期间不良反应发生率。同时记录对比两组患者治疗前后肛肠动力学指标,包括最大收缩压(Anal Maximal Contraction Pressure,AMCP)、肛管最长收缩时间(Anal Longest Contraction Time,ALCT)、直肠静息压(Rectal Rest Pressure,RRP)和肛管静息压(Anal Rest Pressure,ARP)等。结果两组患者治疗后AMCP、ALCT以及不良反应发生率无统计差异性(P>0.05)。观察组治疗后各时间点的VAS评分均低于对照组,GQOLI-74评分、ARP、RRP和疾病缓解率均高于对照组(P<0.05)。结论冰硼痔疮栓治疗可以有效缓解痔病患者肛门疼痛,保护肛门直肠功能,提高生活质量,有益于临床。 Objective Explore the effect of bingboron hemorrhoids suppository on anal pain and quality of life in patients with hemorrhoids.Method A retrospective analysis was conducted on the data of 110 patients with hemorrhoids admitted to the Department of Anorectal Surgery at the Second Traditional Chinese Medicine Hospital of Sichuan Province from December 2019 to January 2021.According to the treatment method,the patients were divided into two groups,with 56 cases in the observation group receiving treatment with bingboron hemorrhoids suppositories,and 54 cases in the control group receiving treatment with Mayinglong musk hemorrhoids suppositories.Compare the Visual Analogue Scale(VAS)score,General Quality of Life Inventory-74(GQOLI-74)score,and disease remission rate of two groups at different time points before and after treatment,and statistically compare the incidence of adverse reactions during hospitalization between the two groups.Simultaneously record and compare anorectal dynamic indicators before and after treatment between two groups of patients,including Maximum Contraction Pressure(AMCP),Anal Longest Contraction Time(ALCT),Rectal Rest Pressure(RRP),and Anal Rest Pressure(ARP).Result There was no statistical difference in the incidence of AMCP,ALCT,and adverse reactions between the two groups of patients after treatment(P>0.05).After treatment,the VAS score of the observation group at all time points was lower than that of the control group,and the GQOLI-74score,ARP,RRP,and disease remission rate were higher than those of the control group(P<0.05).Conclusion Bingboron hemorrhoid suppository treatment can effectively alleviate anal pain in hemorrhoid patients,protect anorectal function,improve quality of life,and is beneficial to clinical practice.
作者 赵希忠 毛红 杨军义 康进 唐平 赵强 江南 ZHAO Xizhong;MAO Hong;YANG Junyi;KANG Jin;TANG Ping;ZHAO Qiang;JIANG Nan(Sichuan Second Hospital of Traditional Chinese Medicine,Chengdu 610014,China;Institute of Medicinal Fungi,Sichuan Academy of Chinese Medicine Science,Chengdu 610015,China)
出处 《四川中医》 2025年第7期134-138,共5页 Journal of Sichuan of Traditional Chinese Medicine
基金 四川省中医药管理局科学技术研究专项(2021MS229)。
关键词 冰硼痔疮栓 痔病 肛门疼痛 生活质量 Bingboron hemorrhoid suppository Hemorrhoids Pain Quality of life
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