摘要
目的通过静脉通道联合穿刺针道推注血凝酶与单独穿刺针道推注血凝酶两种方法,减少低剂量CT引导下经皮肺穿刺活检出血方面,进行疗效对比,得出更优方法,在降低患者受辐射剂量基础上制定更安全有效的方案。方法选取临沂市中心医院2024年5月一2025年1月行低剂量CT引导下经皮肺穿刺活检术患者,根据血凝酶推注方式不同分为双通道组(观察组)和单通道组(对照组),比较两组患者基线资料(性别、年龄、基础肺病、病灶直径、分布、实性占比、强化程度、穿刺深度及时间、良恶性)和肺穿刺后CT图像有无出血、血液弥散距离、血液弥散体积的差异。结果2组患者基线资料差异、出血发生率差异无统计学意义(P>0.05)。双通道组血液弥散距离、弥散体积低于单通道组,差异具有统计学意义(P<0.05)。结论低剂量CT引导下采用双通道推注血凝酶不能减少肺穿刺活检术出血发生率,但能够减少出血量,并能减少血液向周边肺组织弥散,同时能够降低患者术中受照辐射剂量。
Objective To compare the efficacy of dual channel(intravenous channel and puncture needle channel)and single channel(puncture needle channel)of thrombin injection in reducing bleeding during low-dose CT-guided percu-taneous lung biopsy,identify the optimal method,and develop a protocol with improved safety and efficacy while minimiz-ing radiation exposure to patients.Methods Patients who underwent CT-guided percutaneous lung biopsy at Linyi Central Hospital between May 2024 and January 2025 were selected and divided into a dual channel group(observation group)and a single channel group(control group)according to the methods of thrombin injection.The baseline characteristics(sex,age,underlying lung disease,lesion diameter,distribution,proportion of solid lesions,enhancement degree,puncture depth and time,and benign or malignant)and the differences in CT images after lung puncture(bleeding,blood diffusion distance,and blood diffusion volume)were compared between the two groups of patients.Results There were no significant differ-ences in baseline characteristics and bleeding incidence between the two groups of patients(P>0.05).The diffusion dis-tance and volume of blood in the dual channel group were significantly lower than those in the single channel group(P<0.05).ConclusionThe use of dual channel thrombin injection under low-dose CT guidance cannot reduce the incidence of bleeding in lung biopsy,but it can reduce the amount of bleeding,blood diffusion to surrounding lung tissues,and intraoper-ative radiation exposure to patients.
作者
王友纲
孙学任
武伟
WANG Yougang;SUN Xueren;WU wei(Linyi Central Hospital,Linyi 276400,China)
出处
《中国辐射卫生》
2025年第3期363-367,共5页
Chinese Journal of Radiological Health
基金
临沂市重点研发计划项目(医学类)(2024YX0012)。
关键词
体层摄影术
X线计算机
CT引导
肺活检
出血
并发症
Tomography
X-ray computed tomography
CT guidance
Lung biopsy
Bleeding
Complication
