摘要
颞下颌关节骨髓水肿(BME)是一种在MRI上表现为T1低信号、T2高信号的骨髓异常改变, 常见于颞下颌关节骨关节炎患者。研究表明, BME与关节疼痛、关节盘移位及骨质退变密切相关, 但其具体机制尚不完全明确, 可能涉及力学负荷异常、炎症反应及骨代谢失衡等多种因素。尽管BME被认为是骨关节炎的早期征象, 约71.4%的患者疼痛缓解后BME持续存在, 提示其与临床症状的关联具有复杂性。近年来, 先进的MRI技术(如T2 mapping、脂肪抑制序列)提高了BME的检出率, 并有助于评估其动态变化。然而, BME在颞下颌关节紊乱病中的确切作用仍存在争议, 本文从颞下颌关节BME的病因机制、病理、影像学特点、与临床症状相关性等方面作一综述, 为进一步揭示其在疾病进展中的意义, 提出未来研究方向, 并为临床诊疗提供指导。
Bone marrow edema(BME)of the temporomandibular joint is an abnormal change within the bone marrow that appears as low signal intensity on T1-weighted images and high signal intensity on T2-weighted images in MRI.It is commonly seen in patients with temporomandibular joint osteoarthritis.Studies have shown that BME is closely related to joint pain,disc displacement and bony degeneration,but its specific mechanism is not yet fully understood,potentially involving abnormal mechanical loading,inflammatory responses and imbalances in bone metabolism.Although BME is considered an early sign of osteoarthritis,BME persists in approximately 71.4%of patients after pain resolution,suggesting the complexity of its association with clinical symptoms.In recent years,advanced MRI techniques(such as T2 mapping and fat suppression sequences)have improved the detection rate of BME and facilitated the assessment of its dynamic changes.However,the exact role of BME in temporomandibular disorders remains controversial.This article reviews the etiology and mechanism,pathology,imaging characteristics,and correlation with clinical symptoms of BME in the temporomandibular joint,and proposing future research directions to to elucidate its significance in disease progression and to provide guidance for clinical diagnosis and treatment.
作者
宁琦
刘华蔚
许来青
胡敏
Ning Qi;Liu Huawei;Xu Laiqing;Hu Min(Department of Stomatology,the First Medical Centre,Chinese PLA General Hospital,Beijing 100853,China)
出处
《中华口腔医学杂志》
北大核心
2025年第7期781-786,共6页
Chinese Journal of Stomatology
基金
国家重点研发计划(2023YFC2509100)。
关键词
颞下颌关节
骨关节炎
骨髓水肿
磁共振成像
Temporomandibular joint
Osteoarthritis
Bone marrow edema
Magnetic resonance imaging
