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牙髓活力状态的影响因素及评估方法研究进展

Research progress on influencing factors and assessment methods of pulp vitality
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摘要 健康牙髓是保留天然牙并维持其正常功能的关键。活髓保存治疗因其能够最大限度地保留全部或部分牙髓,提高患牙的远期保存率,在临床应用中越来越广泛。牙髓活力状态是活髓保存治疗方案选择以及疗效评估的关键因素。然而,如何准确评估牙髓活力状态,在临床实际操作中依然具有一定的挑战性。牙髓活力状态受多种因素的影响,包括牙髓暴露类型、龋损状态、牙周炎、外伤、治疗因素、年龄及宿主个体差异等。评估牙髓活力状态,不仅需要医生综合考虑病史和临床表征,还需结合牙髓感觉测试、牙髓血流测试、影像学检查以及分子诊断技术等多种辅助手段。未来,评估牙髓活力状态的技术应当朝着椅旁化、可视化和精准化的方向发展,以期达到临床诊断与组织学诊断的高度一致性,从而为患者提供更为准确和有效的治疗方案。 Healthy dental pulp is essential for preserving teeth and maintaining their normal function.Vital pulp therapy(VPT)is widely used in clinical applications because it aims to preserve vital pulp and enhance the long-term survival of teeth.An accurate diagnosis of pulp vitality is a prerequisite for successful VPT.However,accurately assessing pulp viability remains challenging in clinical practice.Pulp viability is influenced by various factors,including the type of pulp exposure,caries status,periodontitis,trauma,treatment factors,patient age,and individual differences.Assessing pulp viability requires a comprehensive consideration of medical history and clinical manifestations,along with a combination of various auxiliary methods,such as pulp sensibility tests,pulp blood flow tests,imaging techniques and molecular diagnostics.In the future,the technology for assessing pulp vitality should evolve toward chairside,visualization,and precision techniques,to achieve consistency between clinical and histological diagnoses,thereby providing patients with the most effective treatment.
作者 朱萧 陈艳琪 钱琳娜 姜定卓 施莹 吴志芳 ZHU Xiao;CHEN Yanqi;QIAN Linna;JIANG Dingzhuo;SHI Ying;WU Zhifang(Stomatology Hospital,School of Stomatology,Zhejiang University School of Medicine,Zhejiang Provincial Clinical Research Center for Oral Diseases,Key Laboratory of Oral Biomedical Research of Zhejiang Province,Cancer Center of Zhejiang University,Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province,Hangzhou 310000,China)
出处 《口腔疾病防治》 2025年第8期690-698,共9页 Journal of Prevention and Treatment for Stomatological Diseases
基金 国家重点研发项目(2022YFC2405900)。
关键词 活髓保存治疗 牙髓活力状态 牙髓暴露类型 龋损状态 宿主个体差异 牙髓感觉测试 牙髓血流检测 分子诊断技术 vital pulp therapy pulp vitality type of pulp exposure caries status individual differences pulp sensibility tests pulp blood flow tests molecular diagnostics
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