摘要
目的采用Meta分析灸法治疗膝骨关节炎(knee osteoarthritis,KOA)的疗效。方法于中国期刊全文数据库(China National Knowledge Infrastructure,CNKI)、中国学术期刊数据库(万方)、中文科技期刊服务数据库(维普)和PubMed中检索灸法治疗KOA的随机对照试验(randomized controlled trial,RCT),检索时间为2014年1月1日至2020年1月31日,由2名研究人员独立提取数据,评估偏倚风险。采用RevMan 5.2软件进行Meta分析。结果共纳入9篇文献,涉及812例患者,所有研究均为低偏倚风险。Meta分析结果显示,治疗组总有效率高于对照组,差异有统计学意义[OR=2.23,95%CI(1.35,3.70),P=0.002];治疗组视觉模拟评分法评分低于对照组,差异有统计学意义[MD=-0.55,95%CI(-0.82,-0.28),P<0.0001];治疗组西安大略和麦克马斯特大学骨关节炎指数评分高于对照组,差异有统计学意义[MD=-4.55,95%CI(-6.64,-2.46),P<0.0001]。结论灸法比其他方法治疗KOA疗效更佳,不良反应更少。
Objective Meta-analysis of the efficacy of moxibustion in the treatment of knee osteoarthritis(KOA).Methods Randomized controlled trials(RCT)of moxibustion in the treatment of KOA were retrieved from China National Knowledge Infrastructure(CNKI),China Academic Journal Database(Wanfang),Chinese Science and Technology Journal Service Database(VIP)and PubMed,the retrieval time was from January 1,2014 to January 31,2020,two researchers independently extracted the data and assessed the risk of bias,Meta-analysis was performed using RevMan 5.2 software.Results A total of 9 literatures and 812 patients were included,all literatures were at low risk of bias.Meta-analysis results showed that the total effective rate of the treatment group was higher than that in the control group,and the difference was statistically significant(OR=2.23,95%CI[1.35,3.70],P=0.002);The score of visual analogue scale in the treatment group was lower than that in the control group,and the difference was statistically significant(MD=-0.55,95%CI[-0.82,-0.28],P<0.0001);the Western Ontario and McMaster University arthritis index score in the treatment group was higher than that in the control group,and the difference was statistically significant(MD=-4.55,95%CI[-6.64,-2.46],P<0.0001).Conclusion Moxibustion is more effective than other methods in the treatment of KOA with fewer adverse reactions.
作者
陈弘严
蔡何凝
陈晓英
刘婷
CHEN Hongyan;CAI Hening;CHEN Xiaoying;LIU Ting(Department of Rehabilitation,The Third People's Hospital of Yibin,Yibin,Sichuan,644000,China;Department of Acupuncture and Moxibustion,Yibin Hospital of Traditional Chinese Medicine,Yibin,Sichuan,644000,China;Department of Orthopedics and Traumatology,Yibin Hospital of Traditional Chinese Medicine,Yibin,Sichuan,644000,China;Department of Rehabilitation Medicine,The First People's Hospital of Yibin,Yibin,Sichuan,644000,China)
出处
《当代医学》
2025年第2期34-39,共6页
Contemporary Medicine
