摘要
目的了解扬州市幽门螺杆菌(H.pylori)的感染率,为本地H.pylori的防治提供参考。方法本研究基于2017年1月至2024年7月由扬州大学附属医院和南京医科大学共同建设的胃镜筛查队列,对纳入的6079例自然人群进行问卷调查和呼气试验检测,利用统计学方法计算人群感染率,并分析感染相关因素。结果扬州市人群总感染率为44.1%。其中饮茶史(χ^(2)=10.281,P=0.001)、食用辛辣食物(χ^(2)=5.098,P=0.024)、食用腌制食物(χ^(2)=6.538,P=0.038)、文化水平(χ^(2)=7.022,P=0.030)、心理生活压力(χ^(2)=7.456,P=0.024)均与H.pylori感染呈正相关。Logistic回归分析显示长期心理压力过大(β=0.159)和长期的饮茶史(β=0.279)是影响H.pylori感染的独立危险因素,定期锻炼(β=-0.140)和食用热的食物(β=-0.406)是预防H.pylori感染的独立保护因素。结论扬州市总体人群H.pylori感染率约为44.1%,其中扬州市区的H.pylori感染率(48.0%)高于扬州农村地区(39.6%)。持续进行体育锻炼并维持情绪的舒缓与愉悦状态,对于降低H.pylori感染率具有积极作用。相反,长期饮用浓茶、摄入辛辣及腌制食品,以及食用过冷的食物,在一定程度上可能提升H.pylori的感染风险。
Objective To understand the infection rate of Helicobacter pylori(H.pylori)in Yangzhou and provide reference for the prevention and control of local H.pylori.Methods Based on the gastroscopy screening cohort jointly constructed by the Affiliated Hospital of Yangzhou University and Nanjing Medical University from January 2017 to July 2024,6,079 included natural subjects underwent questionnaire survey and breath test,using statistical methods to calculate the population infection rate and analyze infection-related factors in this study.Results The total infection rate of Yangzhou population was 44.1%.Among them,the history of tea drinking(χ^(2)=10.281,P=0.001),consumption of spicy food(χ^(2)=5.098,P=0.024),consumption of pickled food(χ^(2)=6.538,P=0.038),cultural level(χ^(2)=7.022,P=0.0300),and psychological life pressure(χ^(2)=7.456,P=0.024)were positively correlated with H.pylori infection.Logistic Regression analysis showed that long-term psychological stress(β=0.159)and long-term history of tea drinking(β=0.279)were independent risk factors for H.pylori infection,while regular exercise(β=-0.140)and consumption of hot food(β=-0.406)were independent protective factors against H.pylori infection.Conclusion The H.pylori infection rate of the overall population in Yangzhou was about 44.1%,and the H.pylori infection rate in Yangzhou(48.0%)is higher than that in rural areas of Yangzhou(39.6%).Continuous physical exercise and maintaining the emotional soothing and pleasant state can have a positive effect on reducing the H.pylori infection rate.In contrast,drinking strong tea,eating spicy and preserved foods,and eating too cold foods may increase the risk of H.pylori infection to some extent.
作者
于越
周本刚
张敏
李瑶瑶
刘卓琪
丁岩冰
YU Yue;ZHOU Bengang;ZHANG Min;LI Yaoyao;LIU Zhuoqi;DING Yanbing(Department of Gastroenterology,The Affiliated Hospital of Yangzhou University,Yangzhou University,Yangzhou 225100,China;Dalian Medical University,Dalian 116000,China)
出处
《现代消化及介入诊疗》
2025年第5期541-546,共6页
Modern Interventional Diagnosis and Treatment in Gastroenterology
基金
国家自然科学基金面上项目(82273084)
国家自然科学基金青年项目(82404358)
扬州市基础研究计划(联合专硕)卫生健康类重点项目(2024-1-05)。
