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免疫正常的颞叶原发性平滑肌瘤1例

Primary temporal lobe leiomyoma in an immunocompetent patient:a case report
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摘要 平滑肌瘤是来源于间充质的良性肿瘤,好发生于平滑肌组织。颅内原发性平滑肌瘤临床罕见,大多数是免疫缺陷患者,而免疫正常者非常罕见。本文报道1例56岁男性,因右额颞部疼痛9个月、加重1个月入院。入院MRI检查显示右侧颞叶团块状等长T1、混杂T2异常信号,增强后不均匀强化,大小约37 mm×25 mm×35 mm,伴瘤周明显水肿。术前胸腹检查未见占位性病变,血清人类免疫缺陷病毒抗体阴性、乙型病毒性肝炎表面抗原阴性。完善术前准备,显微手术切除肿瘤。术中见肿瘤与硬膜有粘连,呈灰色,质韧,血供一般,与周围脑组织界清晰,完全切除肿瘤。术后病理诊断为平滑肌肿瘤。术后头痛消失,恢复良好,随访2年未见肿瘤复发。 Leiomyoma is a benign tumor originating from mesenchymal tissue,commonly occurring in smooth muscle.Primary intracranial leiomyoma is clinically rare and predominantly affects immunocompromised patients,with immunocompetent individuals being exceptionally uncommon.This article reports a case of a 56-year-old male admitted with a 9-month history of right frontotemporal pain that worsened over the previous month.Preoperative MRI revealed a mass in the right temporal lobe exhibiting isointense signal on T1-weighted imaging and heterogeneous hyperintensity on T2-weighted imaging,with heterogeneous enhancement.The lesion measured approximately 37 mm×25 mm×35 mm and was accompanied by significant peritumoral edema.Chest and abdominal examinations showed no space-occupying lesions,and serological tests were negative for HIV antibodies and hepatitis B surface antigen.Following preoperative preparation,the tumor was microsurgically resected.Intraoperatively,the tumor appeared grayish,adhered to the dura,and displayed a firm consistency with moderate blood supply.It was well-demarcated from the surrounding brain tissue and completely excised.Postoperative pathological diagnosis confirmed a smooth muscle tumor.The patient's headache resolved postoperatively,and he recovered well.No tumor recurrence was observed during the 2-year follow-up period.
作者 赵文生 岳宇 茅名凯 ZHAO Wen-sheng;YUE Yu;MAO Ming-kai(Department of Neurosurgery,Hefei BOE Hospital,Hefei 230011,China)
出处 《中国临床神经外科杂志》 2025年第5期315-317,共3页 Chinese Journal of Clinical Neurosurgery
关键词 颅内肿瘤 平滑肌瘤 颞叶 显微手术 免疫正常 Intracranial tumors Leiomyoma Temporal lobe Immunocompetent
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