摘要
目的了解非四川省户籍梅毒感染孕产妇妊娠期治疗情况及影响因素。方法通过国家预防艾滋病、梅毒和乙肝母婴传播信息管理系统,收集2018年1月至2023年12月四川省分娩的非四川省户籍梅毒感染产妇个案登记卡,对不同特征梅毒感染产妇治疗和充分治疗情况进行描述,并采用多因素Logistic回归分析梅毒感染产妇治疗和充分治疗的影响因素。结果1510例梅毒感染孕产妇中,接受治疗的有1470人(97.35%),接受充分治疗的有1318人(89.66%)。2018-2023年,梅毒感染孕产妇的治疗率由94.12%上升至100.00%(χ_(趋势)^(2)=19.245,P<0.05),充分治疗率由83.33%上升至93.72%(χ_(趋势)^(2)=16.354,P<0.05)。多因素Logistic回归分析结果显示,年龄20~35岁(aOR=2.552,95%CI:1.454~3.930)、家务及待业(aOR=1.623,95%CI:1.502~2.582)、产次≤1次(0次aOR=1.809,95%CI:1.338~2.912;1次aOR=1.774,95%CI:1.035~2.266)、孕早/中期诊断妊娠梅毒感染(aOR=2.755,95%CI:1.690~4.858)的孕产妇接受梅毒治疗的概率较高;家务及待业(aOR=1.825,95%CI:1.224~2.318)、产次≤1(0次aOR=2.297,95%CI:1.304~3.125;1次aOR=1.557,95%CI:1.139~2.244)、孕早/中期诊断妊娠梅毒感染(aOR=4.801,95%CI:2.293~7.942)、有既往梅毒感染史(aOR=1.311,95%CI:1.095~1.996)、配偶/性伴未感染梅毒(aOR=1.663,95%CI:1.186~2.325)的孕产妇接受梅毒充分治疗的概率更高。结论非四川省户籍梅毒感染孕产妇治疗比例相对较高,但充分治疗比例有待提升。应重点加强对家务及待业、经产妇和有既往梅毒感染史妇女的健康宣教,加大孕产妇孕早中期梅毒的检测力度,降低梅毒母婴传播。
Objective To investigate the treatment situation and influencing factors among pregnant women with syphilis infection without a registered residence in Sichuan Province.Methods Individual case registration cards of non-Sichuan-registered syphilis-infected pregnant women who delivered in Sichuan Province between January 2018 and December 2023 were collected through the National Information Management System for the Prevention of mother-to-child transmission of human immunodeficiency virus(HIV),syphilis,and hepatitis B.The treatment and adequate treatment status of pregnant women with syphilis were described.Multivariate logistic regression was used to analyze the factors influencing adequate treatment.Results Among 1510 syphilis-infected mothers,1470(97.35%)received treatment and 1318(89.66%)received adequate treatment.From 2018 to 2023,the treatment rate of syphilis-infected increased from 94.12%to 100.00%(χ_(trend)^(2)=19.245,P<0.05),and the adequate treatment rate increased from 83.33%to 93.72%(χ_(trend)^(2)=16.354,P<0.05).Multivariate logistic regression analysis revealed that the probability of receiving treatment during pregnancy was high among syphilis-infected mothers aged 20-35 years(aOR=2.552,95%CI:1.454-3.930),housework and unemployment(aOR=1.623,95%CI:1.502-2.582),no children or only one child(0 time:aOR=1.809,95%CI:1.338-2.912;1 time:aOR=1.774,95%CI:1.035-2.266),and syphilis diagnosis in early or mid-term pregnancy(aOR=2.755,95%CI:1.690-4.858).The probability of receiving adequate treatment was high during pregnancy for syphilis-infected housework and unemployment(aOR=1.825,95%CI:1.224-2.318),no children,or only one child(0 time:aOR=2.297,95%CI:1.304~3.125;1 time:aOR=1.557,95%CI:1.139-2.244),syphilis diagnosis in early or mid-term pregnancy(aOR=4.801,95%Cl:2.293-7.942),previous infection with syphilis(aOR=1.311,95%CI:1.095-1.996),and husband/sexual partner without syphilis(aOR=1.663,95%CI:1.186-2.325).Conclusions The treatment rate for pregnant women with syphilis who were not registered in Sichuan Province was relatively high.However,the proportion of adequate treatment needs to be enhanced.It is essential to prioritize health education for housewives and women who are unemployed or multiparous,and those with a history of syphilis infection.Additionally,the detection of syphilis during the early and mid-pregnancy stages of antenatal care should be intensified to reduce the risk of mother-to-child syphilis transmission.
作者
张莉莉
贾思艳
岳岑
杨茂玲
刘俐
张琰清
刘佳欣
张燕
ZHANG Lili;JIA Siyan;YUE Cen;YANG Maoling;LIU Li;ZHANG Yanqing;LIU Jiaxin;ZHANG Yan(Sichuan Provincial Women's and Children's Hospital/The Affiliated Women's and Children's Hospital of Chengdu Medical College,Chengdu 61004l,Sichuan,China)
出处
《中国艾滋病性病》
北大核心
2025年第6期671-676,共6页
Chinese Journal of Aids & STD
基金
四川省妇幼保健院院内科技创新基金项目(20240315)。
关键词
梅毒
流动孕产妇
治疗
影响因素
syphilis
migrant pregnant women
treatment
influencing factor
