摘要
Polycystic ovary syndrome(PCOS)is a prevalent endocrine disorder among women of reproductive age,with a global prevalence ranging from 5%to 18%(Shrivastava and Conigliaro,2023).Currently,a total of 12.13 million cases of infertility(Liu et al.,2024)and 0.24 million cases of cardiovascular disease(Wan et al.,2024)are attributable to PCOS worldwide,and nearly 8 billion US dollars are spent in the USA and Europe for the management of PCOS every year.However,there are still many challenges in understanding and treatment of PCOS.
基金
supported by the National Key Research and Development Program of China(2021YFC2700403)
Shanghai Municipal Science and Tech-nology Major Project(2023SHZDZX02)
the National Natural Science Foundation of China(81873660 and 32371333)
the Science and Technology Commission of Shanghai Municipality(23XD1423300 and 23ZR1411000).