摘要
目的分析上海市皮肤病医院住院患者浅部真菌病的发病情况及致病真菌的菌种构成,探讨住院患者浅部真菌感染合并皮肤病的情况。方法对2022年10月—2024年10月我院住院部确诊的269例浅部真菌病患者的临床特征及真菌荧光染色镜检和真菌培养结果进行分析。结果269例浅部真菌病患者男性患者占比(75.09%)多于女性(24.91%)。股癣在性别构成上多见于男性(P<0.05)。年龄多分布于61~80岁,甲真菌病在年龄分布上有显著差异(P<0.05)。病种多为足癣和甲真菌病。269例患者仅有86例完善真菌培养,送检率34.94%,分离到的90株菌株中,皮肤癣菌在菌群构成上占优势(42株,46.67%)。住院部浅部真菌感染患者合并的其他皮肤病中,依次为湿疹(41例,15.24%)、丹毒(32例,11.90%)和银屑病(31例,11.52%)。其中,足皮肤细菌感染患者合并的浅部真菌病中足癣占比最多(77.78%),银屑病合并的浅部真菌病中甲真菌病占比最多(38.71%)。结论上海市皮肤病医院住院部患者的浅部真菌病多为足癣和甲真菌病,主要致病菌是红色毛癣菌和白念珠菌,合并其他皮肤病前三位是湿疹、丹毒以及银屑病。
Objective To analyze the incidence and pathogenic fungal species composition of superficial mycoses in inpatients of the Shanghai Skin Disease Hospital,and to explore the co-occurrence of superficial fungal infections with skin diseases in inpatients.Methods The clinical characteristics and results of fungal fluorescence staining microscopy and fungal culture of 269 inpatients diagnosed with superficial mycoses in our hospital from October 2022 to October 2024 were analyzed.Results Among the 269 inpatients with superficial mycoses,male patients accounted for 75.09%,which was higher than female patients(24.91%).There was a significant difference in the gender composition of tinea cruris(P<0.05).The age distribution was mostly between 61 to 80 years old,and there was a significant difference in the age distribution of onychomycosis(P<0.05).The clinical classification was mainly tinea pedis(106 cases,39.41%).Only 86 of the 269 inpatients completed fungal culture,with a submission rate of 34.94%.Among the 90 strains isolated,dermatophytes had an advantage in the composition of the fungal population(42 strains,46.67%).Among the other skin disease complicated by superficial fungal infections in the inpatient department,eczema was the most common(41 cases,15.24%),followed by erysipelas(32 cases,11.90%),and then psoriasis(31 cases,11.52%).Among them,the combination of bacterial skin infection of the foot and tinea pedis had the highest proportion of 77.78%,and the combination of psoriasis and onychomycosis had the highest proportion of 38.71%.Conclusion Tinea pedis and onychomycosis constitute the majority of superficial mycoses in inpatients at the Shanghai Skin Disease Hospital,and the main pathogenic fungi are Trichophyton rubrum and Candida albicans.The top three co-occurring skin diseases are eczema,erysipelas,and psoriasis.
作者
耿礼倩
史娟
倪礼楠
何文婧
戴鹤骏
谭静文
杨连娟
GENG Liqian;SHI Juan;NI Linan;HE Wenjing;DAI Hejun;TAN Jingwen;YANG Lianjuan(Shanghai Skin Disease Hospital,Tongji University School of Medicine,Shanghai 200443,China)
出处
《中国真菌学杂志》
2025年第3期245-250,共6页
Chinese Journal of Mycology
基金
国家自然科学基金(8217121063)。
关键词
浅部真菌病
病原真菌
培养率
superficial mycoses
pathogenic fungi
culture rate
