摘要
血管新生是动脉粥样硬化(As)斑块发展的关键环节,抑制血管新生有助于斑块稳定并降低相关心血管事件风险。载脂蛋白A1结合蛋白(A1BP)是一种重要的分泌蛋白,越来越多的研究表明,其在血管新生的调控中发挥重要作用。该文旨在阐述A1BP对血管新生及心血管疾病的作用机制,为心血管疾病的临床治疗提供新的思路。
Angiogenesis is a key link in the development of atherosclerotic plaques.Inhibiting angiogenesis contributes to plaque stabilization and reduces the risk of related cardiovascular events.Apolipoprotein A1 binding protein(A1BP),an important secretory protein,has been shown in a growing body of research to play a significant role in the regulation of angiogenesis.This article aims to elucidate the mechanisms of action of A1BP on angiogenesis and cardiovascular diseases,thereby providing new perspectives for the clinical treatment of cardiovascular diseases.
作者
萧云
喻思扬
黄琨
陈佳伟
应如
XIAO Yun;YU Siyang;HUANG Kun;CHEN Jiawei;YING Ru(Department of Cardiology,the First Affiliated Hospital of Nanchang University,Nanchang,Jiangxi 330000,China)
出处
《中国动脉硬化杂志》
2025年第8期714-720,共7页
Chinese Journal of Arteriosclerosis
基金
国家自然科学基金项目(82200363)
江西省卫生健康委科技计划项目(202130208)。
