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运动介导心脏保护及其防治心血管疾病相关机制的研究进展

Research progress on exercise-mediated cardioprotection and its mechanisms in the prevention and treatment of cardiovascular diseases
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摘要 运动对心脏保护及心血管健康效益已得到广泛认可。运动通过诱导心肌生理性肥大、改善线粒体代谢、调节心血管自主神经系统平衡状态,提高心肺适能等机制,改善心血管代谢,降低多种心血管疾病发病风险,并在疾病防治中发挥积极作用。运动通过促进相关运动因子分泌,诱导和激活相关信号通路,改善心血管系统的胰岛素敏感性和机体代谢,提高抗氧化能力等途径,对心血管系统结构功能产生良性效应。研究运动对心血管结构功能的积极作用及防治相关疾病机制,对安排合理的运动健康促进行为具有重要理论价值和广阔临床应用前景。 The protective effect of exercise on the heart and its benefits in promoting cardiovascular health have been widely recognized.Exercise induces physiological hypertrophy of the myocardium,improves mitochondrial metabolism and function,regulates the balance of the cardiovascular autonomic nervous system.These mechanisms enhance cardiovascular fitness,improves cardiovascular metabolism and function,and reduce the risk of various cardiovascular diseases,playing a positive biological role in disease prevention and treatment.Exercise also has a beneficial health effect on the structure and function of the cardiovascular system by promoting the secretion of related exercise factors,inducing and activating related signaling pathways,improving insulin sensitivity and metabolism of the cardiovascular system,and enhancing antioxidant capacity.Studying the mechanisms of exercise-mediated benefits on cardiovascular structure and function and its role in disease prevention and treatment offers valuable theoretical insights for designing effective exercise-based health promotion strategies and holds great promise for clinical applications.
作者 罗滨 Luo Bin(School of Medical Technology and Nursing,Shenzhen Polytechnic University,Shenzhen 518055,China)
出处 《解剖学杂志》 2025年第3期252-256,共5页 Chinese Journal of Anatomy
关键词 运动 健康效应 心脏保护 心血管疾病 exercise health effect cardioprotection cardiovascular diseases
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