摘要
目的 分析老年女性骨质疏松症(osteoporosis,OP)住院患者衰弱及营养风险的现状,探讨老年女性OP住院患者衰弱与营养风险的相关性。方法 选取2022年4月—2023年4月福建省漳州市医院收治的老年女性OP住院患者60例为研究对象,采用临床衰弱评估表(clinical frailty scale,CFS-09)评估患者的躯体功能,并使用营养风险筛查2002(nutrition risk screening 2002,NRS2002)评估患者的营养风险,收集患者的一般资料及血清白蛋白(albumin,ALB)、超敏C反应蛋白(high-sensitivity C-reactive protein,hs-CRP),分析老年女性OP住院患者衰弱与营养风险的相关性及衰弱的影响因素。结果 60例老年女性OP住院患者中,衰弱患病率为60%(36/60),营养风险发生率50%(30/60),且营养风险与衰弱存在正相关性(P<0.05)。衰弱组的年龄为(73.6±5.3)岁,大于非衰弱组的(68.7±3.6)岁,年龄校正查尔森合并症指数(age-adjusted Charlson comorbidity index,aCCI)、hs-CRP水平分别为5.0(4.1,5.5)分、(4.1±1.3)mg/L,高于非衰弱组的4.0(3.0,4.0)分、(1.8±1.3)mg/L,有营养风险者占比66.7%,高于非衰弱组的25.0%,运动者占比22.2%,低于非衰弱组的79.2%,身体质量指数(body mass index,BMI)、血清ALB水平分别为(18.9±1.3)kg/m^(2)、(33.7±2.2)g/L,低于非衰弱组的(21.1±1.6)kg/m^(2)、(36.6±1.7)g/L,差异均有统计学意义(P<0.05)。进一步通过logistic回归分析,提示营养风险、hs-CRP是老年女性OP住院患者的独立危险因素,血清ALB水平是其独立保护因素。结论 老年女性OP住院患者有较高的营养风险和衰弱发生率,营养风险与衰弱之间存在正相关性。营养风险、hs-CRP、血清ALB是影响老年女性OP住院患者衰弱的独立影响因素,需引起重视和深入研究。
Objective To analyze the current status of frailty and the nutritional risk of elderly female inpatients with osteoporosis(OP),and to explore the correlation between frailty and nutritional risk in elderly female inpatients with OP.Methods From April 2022 to April 2023,a total of 60 elderly female inpatients with OP admitted to Zhangzhou Municipal Hospital of Fujian Province were selected as the research subjects.The clinical frailty scale(CFS-09)was used to evaluate the physical function of the patients and nutritional risk screening 2002(NRS2002)was used to assess the patients'nutritional risk.General information and serum albumin(ALB),high-sensitivity C-reactive protein(hs-CRP)were collected to analyze the correlation between frailty and nutritional risk in elderly female inpatients with OP,as well as the influencing factors of frailty.Results Among the 60 elderly female inpatients with OP,60%(36/60)had frailty and 50%(30/60)had nutritional risk,with a positive correlation between nutritional risk and frailty(P<0.05).The age of the frailty group was(73.6±5.3)years,which was higher than that of the non-frailty group at(68.7±3.6)years.The age-adjusted Charlson comorbidity index(aCCI)and hs-CRP levels of the frailty group were 5.0(4.1,5.5)points and(4.1±13.)mg/L,respectively,which were higher than those of the non-frailty group,which were 4.0(3.0,4.0)points and(1.8±1.3)mg/L.The proportion of individuals at nutritional risk of the frailty group was 66.7%,which was higher than the non-frailty group's 25.0%.The proportion of individuals with physical exercise of the frailty group was 22.2%,which was lower than the non-frailty group's 79.2%.The body mass index(BMI)and serum ALB levels of the frailty group were(18.9±1.3)kg/m^(2) and(33.7±2.2)g/L,were lower than those of the non-frailty group,which were(21.1±1.6)kg/m^(2) and(36.6±1.7)g/L.The differences were all statistically significant(P<0.05).Further logistic regression analysis suggests that nutritional risk and hs-CRP were independent risk factors for elderly female inpatients with OP,while serum ALB levels were the independent protective factor.Conclusion Elderly female inpatients with OP have a higher nutritional risk and incidence of frailty,and there is a positive correlation between nutritional risk and frailty.Nutritional risk,hs-CRP and serum ALB are independent influencing factors affecting frailty in elderly female inpatients with OP,which require attention and in-depth research.
作者
林小芬
张惠琼
LIN Xiaofen;ZHANG Huiqiong(Department of Geriatric Medicine,Zhangzhou Municipal Hospital of Fujian Province,Zhangzhou Fujian 363000,China)
出处
《中国卫生标准管理》
2025年第9期37-40,共4页
China Health Standard Management
