摘要
目的 探讨胎膜早破的胎盘病理特征及与新生儿不良预后之间的关联性。方法 选取2021年1月—2023年9月安顺市妇幼保健院接收的289例胎膜早破产妇作为本次研究的观察组,另选取相同时间段内的300例正常产妇作为本次研究的对照组,就2组产妇的胎盘病理特征和新生儿的预后情况进行对比和原因分析。结果 观察组绒毛间质纤维化的发生率为16.96%,绒毛膜羊膜炎的发生率为11.42%,胎盘梗死的发生率为5.88%,对照组分别为0.67%、0、0.33%,观察组各项均高于对照组,差异均有统计学意义(P<0.05);观察组新生儿窒息发生率为9.00%,感染发生率为9.34%,总发生率为23.88%,对照组分别为1.00%、3.67%和8.00%,观察组高于对照组,差异均有统计学意义(P<0.05)。结论 相对于正常产妇,胎膜早破的产妇易见绒毛间质纤维化、绒毛膜羊膜炎和胎盘梗死等病理特征,同时胎膜早破也是造成各种新生儿不良事件的原因之一,须作针对性的医疗干预。
Objective To explore the pathological characteristics of placenta with premature rupture of membranes and its correlation with poor prognosis of newborns.Methods From January 2021 to September 2023,a total of 289 pregnant women with premature rupture of membranes received by Anshun Maternal and Child Health Care Children's Hospital were selected as the observation group of this study,and 300 normal pregnant women were selected as the control group of this study.The pathological characteristics of placenta and the prognosis of newborns in the two groups were compared and analyzed.Results The incidence of villus interstitial fibrosis in the observation group was 16.96%,the incidence of chorioamnionitis was 11.42%,and the incidence of placental infarction was 5.88%.In the control group,the corresponding values were 0.67%,0,and 0.33%.The observation group had higher incidences than the control group,with statistically significant differences(P<0.05).In the observation group,the neonatal asphyxia was 9.00%,infection was 9.34%,and the total incidence was 23.88%.In the control group,these figures were 1.00%,3.67%,and 8.00%,respectively.The observation group showed higher incidences than the control group,with statistically significant differences(P<0.05).Conclusion Compared with normal pregnant women,pregnant women with premature rupture of membranes are more likely to see pathological features such as chorionic fibrosis,chorioamnionitis and placental infarction.At the same time,premature rupture of membranes is also one of the causes of various adverse events in newborns,which requires targeted medical intervention.
作者
张霞
杨娟
范远芳
ZHANG Xia;YANG Juan;FAN Yuanfang(Department of Pathology,Anshun Maternal and Child Health Care Children's Hospital,Anshun Guizhou 561000,China)
出处
《中国卫生标准管理》
2025年第9期19-22,共4页
China Health Standard Management
关键词
胎膜早破
病理特征
绒毛间质纤维化
绒毛膜羊膜炎
胎盘梗死
不良预后
premature rupture of membranes
pathological features
villous interstitial fibrosis
chorionic amnionitis
placental infarction
adverse prognosis
