摘要
目的探讨中国中老年人群睡眠时长对心血管疾病(cardiovascular disease,CVD)发病风险的影响。方法利用2011—2020年中国健康与养老追踪调查数据,纳入≥45岁基础信息及随访信息完善的8446名中老年人为研究对象,根据睡眠时长将入组人群分为0~<7 h组、7~9 h组、>9 h组,采用Kaplan-Meier法、Log-rank检验、Cox半参数模型、限制性立方样条(restricted cubic spline,RCS)模型进行统计分析,观察睡眠时长对CVD发病的影响。结果2011—2020年,我国中老年人群CVD的发病密度为3.02%;Kaplan-Meier生存曲线结果显示,每天睡眠时长0~<7 h组的人群CVD累计发病风险最高(χ^(2)=15.43,P<0.01);Cox半参数模型显示,与睡眠时间7~9 h组的中老年人相比,睡眠时长0~<7 h组CVD患病风险增高(HR=1.14,95%CI:1.04~1.24),睡眠时长>9 h组的中老年人患CVD的风险与7~9 h组差异无统计学意义(HR=1.03,95%CI:0.96~1.11)。RCS结果显示,当睡眠时长>2.5 h时,睡眠时长与CVD发病风险大致呈“L”型相关(χ^(2)=6.42,P=0.04)。结论睡眠时长0~<7 h会增加中国中老年人群患CVD的风险,睡眠时长>9 h不会增加CVD患病风险。
Objective To explore the effect of sleep duration on cardiovascular disease(CVD)among the middle-aged and el-derly individuals in China.Methods Using data from the China Health and Retirement Longitudinal Study(CHARLS)from 2011 to 2020,a total of 8446 participants aged 45 and above with complete baseline and follow-up information were included in the study.According to sleep duration,the enrolled population was divided into O-<7 h group,7-9 h group,and>9 h group.Statistical analysis was conducted using the Kaplan-Meier survival curves,Log-rank tests,Cox proportional hazards models,and restricted cubic spline(RCS)models to assess the impact of sleep duration on the incidence of CVD.Results From 2011 to 2020,the incidence density of CVD among the middle-aged and elderly population in China was 3.02%.Kaplan-Meier sur-vival curve results indicated that the cumulative risk of cardiovascular disease is highest for those with a daily sleep duration O-<7 h(x?=15.43,P<0.01).The Cox proportional hazards model revealed that compared to those sleeping 7-9 h,individuals in the 0-<7 h group had an increased risk of developing CVD(HR=1.14,95%CI:1.04-1.24),while the risk for those sleep-ing>9 h was not statistically different from the 7-9 h group(HR=1.03,95%CI:0.96-1.11).RCS analysis indicated that when sleep duration exceeded 2.5 hours,there was an approximately"L"-shaped relationship between sleep duration and CVD risk(χ^(2)-6.42,P=0.04).Conclusions Sleep duration 0-<7 h willincrease the risk of cardiovascular disease among middle-aged and elderly Chinese individuals,while sleep duration>9 h will not increase the risk of cardiovascular disease.
作者
罗玉霞
张小春
舒婷
兰莉
LUO Yuxia;ZHANG Xiaochun;SHU Ting;LAN Li(School of Clinical Medicine,North Sichuan Medical College,Nanchong,Sichuan 637100,China)
出处
《中国预防医学杂志》
2025年第6期697-702,共6页
Chinese Preventive Medicine
基金
四川省医学会2024年度伤口和慢病(泰阁)专项科研项目(2024TG35)。
关键词
中老年人群
睡眠时长
心血管疾病
中国健康与养老追踪调查
队列研究
Middle-aged and elderly people
Sleep duration
Cardiovascular diseases
China Health and Retirement Longitudinal Study
Cohort study
