摘要
目的分析北京市某三级甲等肿瘤专科类医院10年间鼻咽癌患者随访数据,为鼻咽癌的防治提供参考。方法选取2009年1月1日—2018年12月31日某院收治的2141例鼻咽癌患者病案随访数据,通过二次电话随访确保总体有效随访率>90%。采用ICD-10和ICD-O分类,使用单因素方差分析、χ^(2)/Fisher检验比较不同组别差异,Cochran-Armitage趋势性检验结合分析随访结果、时间、年龄、性别、分布特征及变化趋势。结果2009-2018年鼻咽癌患者的总体5年期病案随访生存率为74.1%。生存率在10年间呈上升趋势,患者生存率随年龄升高呈现下降趋势,男性的生存率低于女性。肿瘤部位中鼻咽多壁患者生存率最高,为77.9%,肿瘤病理分类中鳞状细胞肿瘤生存率最高,为74.5%。肿瘤分期中Ⅰ期患者的5年期生存率最高,为92.6%,Ⅳ期最低,为59.1%。初治方式中放射治疗的患者生存率最高,为80.2%,手术及操作生存率最低,为50.5%。结论随访患者构成、疾病特点、随访结果等与我国鼻咽癌的相关文献报道一致,医院应及时评估治疗效果、早期发现复发及转移灶、检测和处理治疗相关并发症、促进功能康复,提高鼻咽癌患者的生存率。
Objectives This study aims to analyze the follow-up data of nasopharyngeal carcinoma patients in a tertiary-level A-class tumor specialist hospital in Beijing over the past 10 years and provide a reference for the prevention and treatment of nasopharyngeal carcinoma.Methods The medical record follow-up data of 2,141 patients with nasopharyngeal carcinoma admitted to a certain hospital from January 1,2009 to December 31,2018 were selected,and a second telephone follow-up was conducted to ensure that the overall effective follow-up rate was>90%.ICD-10 and ICD-O classification were used.One-way analysis of variance and χ^(2)/Fisher test were used to compare the differences among different groups.Cochran-Armitage trend test was used to analyze the follow-up results,time,age,gender,distribution characteristics and change trends.Results The overall 5-year survival rate of medical records follow-up in NPC patients from 2009 to 2018 was 74.1%.The survival rate showed an upward trend over the past 10 years,and then decreased with increasing age.The survival rate of men was lower than that of women.Among tumor locations,patients with nasopharyngeal multi-wall tumors had the highest survival rate,at 77.9%,and among tumor pathological classifications,patients with squamous cell tumors had the highest survival rate,at 74.5%.Among the tumor stages,the 5-year survival rate was the highest for patients in stageⅠ,at 92.6%,and the lowest for patients in stageⅣ,at 59.1%.Among the primary treatments,the survival rate of patients receiving radiotherapy was the highest,at 80.2%,while the survival rate of patients receiving surgery and manipulation was the lowest,at 50.5%.Conclusions The patient composition,disease characteristics,and follow-up Results of the follow-up patients were consistent with those reported in the relevant literature on nasopharyngeal carcinoma in our country.Hospitals should promptly evaluate treatment outcomes,detect recurrence and metastasis at an early stage,detect and manage treatment-related complications,promote functional rehabilitation,and improve the survival rate of NPC patients.
作者
王凯鹏
马宇娇
杨爱平
杨景芳
刘爽
霍宇艳
Wang Kaipeng;Ma Yujiao;Yang Aiping;Yang Jingfang;Liu Shuang;Huo Yuyan(National Cancer Center,National Clinical Research Center for Cancer,Medical Records Office,Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China;不详)
出处
《中国病案》
2025年第5期59-63,共5页
Chinese Medical Record
关键词
鼻咽癌
病案
随访
疾病构成
生存分析
Nasopharyngeal carcinoma
Medical records
Follow-up
Disease composition
Survival analysis
