摘要
目的分析咽鼓管球囊扩张技术联合压力雾化鼻腔疗法在成人分泌性中耳炎治疗中的临床效果。方法采用前瞻性研究,选取2020年1月至2023年1月在陕西省人民医院接受诊疗的102例成人分泌性中耳炎患者,通过随机数字表法分为参照组(采用咽鼓管球囊扩张术治疗)和联合组(在参照组基础上联合压力雾化鼻腔治疗)。联合组51例,男29例、女22例,年龄(38.26±5.16)岁,病程(4.36±0.47)年;21例左侧,30例右侧;参照组51例,男27例、女24例,年龄(39.87±4.97)岁,病程(4.42±0.51)年;23例左侧,28例右侧。比较两组患者的临床疗效、听力功能、咽鼓管功能相关指标[咽鼓管功能评分量表(ETS-5)与七项咽鼓管功能障碍症状评分量表(ETDQ-7)]、生活质量[中文版慢性耳病调查量表(CCES)]及不良反应和复发率。采用t检验、χ^(2)检验进行统计分析。结果联合组的总有效率为96.08%(49/51),高于参照组的82.35%(42/51),差异有统计学意义(P<0.05)。治疗后,联合组患者的气导听阈、骨导听阈、气骨导差均低于参照组(均P<0.05);联合组患者的ETS-5评分以及CCES各项评分高于参照组,ETDQ-7评分低于参照组(均P<0.05)。联合组的不良事件发生率与参照组比较,差异无统计学意义(P>0.05)。联合组的复发率低于参照组[1.96%(1/51)比15.69%(8/51)],差异有统计学意义(P<0.05)。结论咽鼓管扩张技术联合鼻腔压力雾化疗法在成人分泌性中耳炎的治疗中展现出显著优势,治疗安全性高。
Objective To investigate the clinical efficacy of balloon dilation eustachian tuboplasty combined with nasal nebulization in the treatment of adults with secretory otitis media.Methods A prospective study was conducted on 102 adult patients with secretory otitis media treated at Shaanxi Provincial People's Hospital from January 2020 to January 2023.They were divided into a reference group,treated with balloon dilation eustachian tuboplasty,and a combined group,treated with balloon dilation eustachian tuboplasty and pressurized nasal nebulization,by the random number table method,with 51 cases in each group.The combined group consisted of 29 males and 22 females;they were(38.26±5.16)years old;their disease duration was(4.36±0.47)years;affected sides:21 left and 30 right.The reference group consisted of 27 males and 24 females;they were(39.87±4.97)years old;their disease duration was(4.42±0.51)years;affected sides:23 left and 28 right.The clinical efficacies,hearing function,Eustachian tube function[Eustachian Tube Score-5(ETS-5)and Eustachian Tube Dysfunction Questionnaire-7(ETDQ-7)],quality of life[Chinese version of the Chronic Ear Survey(CCES)],adverse events,and recurrence rates were compared between the two groups.Statistical analyses were performed using t tests andχ^(2)tests.Results The overall efficacy rate in the combined group was higher than that in the reference group[96.08%(49/51)vs.82.35%(42/51)],with a statistical difference(P<0.05).After the treatment,the air conduction threshold,bone conduction threshold,and air-bone gap in the combined group were lower than those in the reference group(all P<0.05);The scores of ETS-5 and CCES in the combined group were higher than those in the reference group,while the score of ETDQ-7 was lower(all P<0.05).There was no statistical difference in the incidence rate of adverse events between the two groups(P>0.05).The recurrence rate of combined group was lower than that of the reference group[1.96%(1/51)vs.15.69%(8/51)],with a statistical difference(P<0.05).Conclusion Balloon dilation eustachian tuboplasty combined with nasal nebulization in the treatment of adults with secretory otitis media is effective and safe.
作者
李世东
杨启梅
贠勇刚
Li Shidong;Yang Qimei;Yun Yonggang(Department of Otolaryngology,Head,and Neck Surgery,Shaanxi Provincial People's Hospital,Xi'an 710068,China)
出处
《国际医药卫生导报》
2025年第14期2378-2382,共5页
International Medicine and Health Guidance News
基金
陕西省创新能力支撑计划(2022TD-51)
陕西省重点研发计划(2023-YBSF-081)。
关键词
分泌性中耳炎
咽鼓管球囊扩张术
压力雾化鼻腔治疗
听力功能
生活质量
Secretory otitis media
Balloon dilation eustachian tuboplasty
Pressurized nasal nebulization
Hearing function
Quality of life
