摘要
目的:探讨盆底超声参数联合血清松弛素H_(2)、血清骨桥蛋白(OPN)水平检测对产后压力性尿失禁(PSUI)的预测价值。方法:回顾性选取2021年4月至2024年3月于洛阳市妇幼保健院分娩的90例产妇为研究对象,根据产后是否发生PSUI,分为PSUI组(n=37)、非PSUI组(n=53);对比两组入院时盆底超声参数及血清松弛素H_(2)、OPN水平。根据患者病情程度分为轻度及中重度组,对比不同病情程度患者入院时盆底超声参数及血清松弛素H_(2)、OPN水平,分析盆底超声参数及血清松弛素H_(2)、OPN水平与患者病情程度的相关性及对产后发生PSUI的预测价值及危险度。结果:PSUI组参数膀胱颈移动度(BND)、尿道旋转角度(URA)及血清松驰素H_(2)、OPN水平均高于非PSUI组(P<0.05);轻度患者参数BND、URA及松弛素H_(2)、OPN水平均低于中重度患者(P<0.05);参数BND、URA及血清松弛素H_(2)、OPN水平均与患者病情程度呈正相关(P<0.05);参数BND、URA及血清松弛素H_(2)、OPN水平单独预测产妇发生PSUI的效能分别为0.799、0.805、0.796、0.766,其联合预测产妇发生PSUI的效能为0.933。结论:盆底超声参数及血清松弛素H_(2)、OPN均与产后PSUI疾病严重程度有关,其联合预测PSUI的效能较高,值得临床予以重视。
Objective:To explore the predictive value of pelvic floor ultrasound parameters combined with serum relaxin H_(2)and osteopontin(OPN)levels for postpartum stress urinary incontinence(PSUI).Methods:From April 2021 to March 2024,90 postpartum women who delivered at Luoyang Maternal and Child Health Hospital were retrospectively selected as study subjects.According to whether PSUI occurred postpartum,they were divided into a PSUI group(n=37)and a non-PSUI group(n=53).Pelvic floor ultrasound parameters and serum relaxin H_(2)and OPN levels were compared between the two groups upon admission.Based on the severity of the condition,patients were further divided into mild and moderate-to-severe groups,and pelvic floor ultrasound parameters and serum relaxin H_(2)and OPN levels were compared between these groups.The correlation between pelvic floor ultrasound parameters,serum relaxin H_(2),OPN levels and the severity of the condition,as well as their predictive value and risk for the occurrence of PSUI postpartum,were analyzed.Results:In the PSUI group,bladder neck descent(BND),urethral rotation angle(URA),and serum levels of H_(2)and OPN were all higher than those in the non-PSUI group(P<0.05).In mild cases,BND,URA,and serum levels of relaxin H_(2)and OPN were all lower than those in moderate-to-severe cases(P<0.05).BND,URA,and serum levels of relaxin H_(2)and OPN were all positively correlated with the severity of the condition(P<0.05).The individual predictive efficacies of BND,URA,and serum levels of relaxin H_(2)and OPN for the occurrence of PSUI in postpartum women were 0.799,0.805,0.796 and 0.766,respectively,while their combined predictive efficacy was 0.933.Conclusion:Pelvic floor ultrasound parameters and serum relaxin H_(2)and OPN levels are all associated with the severity of postpartum PSUI,and their combined predictive efficacy for PSUI is high,which deserves clinical attention.
作者
李晶
史洁
单小玲
LI Jing;SHI Jie;SHAN Xiaoling(Department of Ultrasound,Luoyang Maternal and Child Health Hospital,Luoyang 471000,China)
出处
《黑龙江医药科学》
2025年第7期8-11,共4页
Heilongjiang Medicine and Pharmacy
基金
河南省医学科技攻关联合共建项目,编号:LHGJ20192347。
