摘要
自2019年第1版《中国狼疮肾炎诊断和治疗指南》发布以来,国内外在狼疮肾炎诊断、治疗和管理方面取得很多研究进展,获得了大量新的循证医学证据,有必要对该指南进行更新。为此,国家肾脏疾病临床医学研究中心组建由多学科专家组成的指南工作组制订了《中国狼疮肾炎诊治和管理指南(2025版)》,采用推荐意见分级的评估、制订与评价(GRADE)分级对证据质量和推荐意见强度进行分级,以“推荐意见”及“实践建议”的形式来呈现。新版指南重点更新了狼疮肾炎的诱导和维持治疗、特殊类型和难治性狼疮肾炎的治疗,增加了狼疮肾炎患者管理及并发症的评估和治疗,以期为临床医师在治疗决策和疾病管理方面提供指导和参考。
Since the first edition of"Chinese guideline for the diagnosis and treatment of lupus nephritis"launched in 2019,extensive clinical research has been conducted both domestically and internationally regarding the diagnosis,treatment and management of lupus nephritis,yielding substantial new evidence.Therefore,it is necessary to update the guideline.To this end,a guideline working group consisting of multidisciplinary experts was convened and the Grading of Recommendations Assessment,Development,and Evaluation(GRADE)system were employed to rate the quality of evidence and the strength of recommendations,in the form of"Recommendation"and"Practical point".The"Chinese guideline for the diagnosis,treatment and management of lupus nephritis(2025)"focused on updating the induction and maintenance treatment of lupus nephritis,and the treatment of special classes and refractory lupus nephritis.It also included the management of patients with lupus nephritis and the assessment and treatment of relevant complications.The current guideline aims to provide guidance and reference for clinicians in treatment decision-making and disease management.
作者
中国狼疮肾炎诊治和管理指南工作组
国家肾脏疾病临床医学研究中心
刘志红
Working Group for the Chinese Guideline for the Diagnosis,Treatment and Management of Lupus Nephritis;National Clinical Research Centre for Kidney Diseases;Liu Zhihong(不详;National Clinical Research Center for Kidney Diseases,Jinling Hospital,Nanjing 210016,China)
出处
《中华医学杂志》
北大核心
2025年第22期1783-1819,共37页
National Medical Journal of China
基金
国家自然科学基金专项项目(32141004)
国家重点研发计划(2021YFC2501302)。
关键词
狼疮肾炎
诊断
治疗
管理
指南
Lupus nephritis
Diagnosis
Treatment
Management
Guideline
